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Lithium monitoring before and after the distribution of clinical practice guidelines
- John M. Eagles, Ian McCann, T. Neil, N. MacLeod, N. Paterson
- Acta psychiatrica Scandinavica
- 1 May 2000
Objective: To determine whether distribution of clinical practice guidelines improves lithium monitoring and whether standards of monitoring differed between patients in psychiatric contact and those… Expand
Predictors of pulmonary exacerbations in patients with cystic fibrosis infected with multi-resistant bacteria
Background: This study examined characteristics of adult and adolescent patients with cystic fibrosis (CF) to determine factors associated with an increased risk of pulmonary exacerbations. Methods:… Expand
Genetic Deletion of Transglutaminase 2 Does Not Rescue the Phenotypic Deficits Observed in R6/2 and zQ175 Mouse Models of Huntington's Disease
Huntington's disease (HD) is an autosomal dominant, progressive neurodegenerative disorder caused by expansion of CAG repeats in the huntingtin gene. Tissue transglutaminase 2 (TG2), a… Expand
Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem.
- C. Vinkers, B. Olivier, +5 authors N. Paterson
- Chemistry, Medicine
- European journal of pharmacology
- 1 October 2011
There is increased understanding that distinct GABA(A) receptor subtypes mediate different effects of classical benzodiazepines. Here, we aimed to define the contributions of α(1)-containing subtypes… Expand
A mixed fixed ratio/progressive ratio procedure reveals an apathy phenotype in the BAC HD and the z_Q175 KI mouse models of Huntington’s disease
Apathy, characterized by generally reduced interest in and likelihood to perform goal-directed actions, is a recognized symptom of Huntington’s disease (HD), a devastating neurological disorder… Expand
Regenerating the periodontium.
UNLABELLED A variety of techniques have been used in an attempt to regenerate periodontal tissues. Studies have confirmed that considerable but varying amounts of new connective tissue attachment may… Expand
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci
- J. Briliūtė, Paulina A. Urbanowicz, +10 authors Lucy I. Crouch
- Biology, Medicine
- Nature Microbiology
- 3 June 2019
Glycans are the major carbon sources available to the human colonic microbiota. Numerous N-glycosylated proteins are found in the human gut, from both dietary and host sources, including… Expand
COPPER(II) AND NICKEL(II) COMPLEXES OF DIANIONIC AND TETRAANIONIC DINUCLEATING MACROCYCLES
- K. K. Nanda, A. Addison, N. Paterson, E. Sinn, L. K. Thompson, Ushio Sakaguchi
- 20 February 1998
With nickel(II) or copper(II) acetate, 2,6-bis(acetoximato)-4-methylphenol (H2Damox) and 2,6-bis(acetoximato)-4-tert-butylphenol (H2Dabox) afford molecular dinuclear complexes [Cu2(Damox)2] (1), [N...
A mixed fixed ratio/progressive ratio procedure reveals an apathy phenotype in the BAC HD and the z_Q175 KI mouse models of Huntington's disease.
Apathy, characterized by generally reduced interest in and likelihood to perform goal-directed actions, is a recognized symptom of Huntington's disease (HD), a devastating neurological disorder… Expand