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CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases
- K. Bettayeb, N. Oumata, L. Meijer
- Biology, ChemistryOncogene
- 23 June 2008
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TRPC6 channel translocation into phagosomal membrane augments phagosomal function
- V. Riazanski, A. Gabdoulkhakova, D. Nelson
- Biology, MedicineProceedings of the National Academy of Sciences
- 10 November 2015
TLDR
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.
- N. Oumata, K. Bettayeb, H. Galons
- Biology, ChemistryJournal of medicinal chemistry
- 13 August 2008
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CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD
- N. Bukanov, Sarah E. Moreno, O. Ibraghimov-Beskrovnaya
- Biology, MedicineCell cycle
- 3 October 2012
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CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells.
- K. Bettayeb, Dianne Baunbæk, L. Meijer
- BiologyGenes & cancer
- 1 April 2010
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Cyclin-dependent kinase inhibitors closer to market launch?
- H. Galons, N. Oumata, O. Gloulou, L. Meijer
- Biology, ChemistryExpert opinion on therapeutic patents
- 18 July 2013
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Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease?
- A. Hochard, N. Oumata, L. Meijer
- Biology, ChemistryJournal of Alzheimer's disease : JAD
- 2013
TLDR
Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles.
- P. Nguyen, N. Oumata, C. Voisset
- Chemistry, BiologyEuropean journal of medicinal chemistry
- 23 July 2014
Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor.
- Lyamin Z Bendjeddou, N. Loaëc, N. Oumata
- Biology, ChemistryEuropean journal of medicinal chemistry
- 5 January 2017
Cyclin-dependent kinase inhibitors: a survey of recent patent literature
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