• Publications
  • Influence
Plasma Free Amino Acid Profiling of Five Types of Cancer Patients and Its Application for Early Detection
TLDR
It is suggested that PFAA profiling has great potential for improving cancer screening and diagnosis and understanding disease pathogenesis, which involves a relatively simple plasma assay and imposes a lower physical burden on subjects when compared to existing screening methods.
Association between high serum alanine aminotransferase levels and more rapid development and higher rate of incidence of hepatocellular carcinoma in patients with hepatitis C virus‐associated
TLDR
The question of whether the persistent elevation of serum alanine aminotransferase levels (which represents the inflammatory necrosis of hepatocytes) correlates with the development of hepatocellular carcinoma (HCC) was studied in patients with early stage hepatitis C virus‐associated cirrhosis.
Reproducibility and Validity of a Self-administered Food Frequency Questionnaire Used in the JACC Study
TLDR
The FFQ is suitable to deal with a large group of subjects, however, since the energy and the amount of nutrient intake from this FFQ can not show the overall dietary intake situation, the subjects’ dietary intake should be assessed by categories.
Validity of positron emission tomography using fluoro‐2‐deoxyglucose for the preoperative evaluation of endometrial cancer
TLDR
It was found that FDG-PET could not identify any lymph node metastasis less than 1 cm in diameter; therefore, a negative finding of lymph nodes metastasis on FDG -PET should not be interpreted as a reason for omitting retroperitoneal lymph node dissection for the precise surgical staging of endometrial cancer.
Amino acid profile index for early detection of endometrial cancer: verification as a novel diagnostic marker
TLDR
The sensitivity and disease specificity of API for early-stage detection of endometrial cancer was superior to CA125, and this novel plasma biomarker has the potential to become a diagnostic and screening marker for endometricrial cancer.
U‐shaped Effect of Drinking and Linear Effect of Smoking on Risk for Stomach Cancer in Japan
TLDR
Smoking seems to exert a linear effect and drinking, a J‐ or U‐shaped effect on risk for stomach cancer, although there might be a dip of risk in light smokers among female subjects.
The associations between RAS mutations and clinical characteristics in follicular thyroid tumors: new insights from a single center and a large patient cohort.
TLDR
The possibility that follicular adenomas with the RAS mutations have an inherent malignant potential is raised, however, the clinical significance of this finding should be further investigated in more patients and over a longer follow-up period.
Reduction of prostate motion by removal of gas in rectum during radiotherapy.
TLDR
Using rectal gas removal, the cross-sectional area could be decreased, resulting in reduced motion and margins for the prostate and seminal vesicles, especially for WPRT patients who require RT to the prostate, seminal vESicles, and pelvic lymph nodes.
Evaluation of a clinic-based screening program for lung cancer with a case-control design in Kanagawa, Japan.
TLDR
It is demonstrated that screening for lung cancer by family physicians can reduce the lung cancer mortality, and that a clinic-based screening program by family Physicians is effective.
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