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Cell adhesion molecules - can they be used to predict coronary artery disease in patients with familial hypercholesterolaemia?
Adhesion of leukocytes to endothelial cells via cell adhesion molecules (CAMS) is thought to be pivotal in the initiation of atherosclerosis. As patients with familial hypercholesterolaemia (FH) areExpand
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The relationship between insulin sensitivity and serum adiponectin levels in three population groups.
Reduced plasma adiponectin levels are associated with insulin resistance. Black South Africans, like African Americans, are more insulin-resistant than BMI-matched white subjects, as are AsianExpand
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The influence of metabolic syndrome components on plasma PAI-1 concentrations is modified by the PAI-1 4G/5G genotype and ethnicity.
Coronary artery disease (CAD) is less common in African than Indian or White subjects and elevated plasminogen activator inhibitor (PAI)-1 levels may be a risk factor for CAD. Therefore, PAI-1 levelsExpand
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Platelet hyperreactivity in hyperlipidaemia with specific reference to platelet lipids and fatty acid composition.
  • N. Chetty, N. Naran
  • Chemistry, Medicine
  • Clinica chimica acta; international journal of…
  • 31 December 1992
Platelet function after thrombin stimulation, the fatty acid composition of individual phospholipids, and levels of lipid components (cholesterol, cholesterol ester, phospholipids and triglycerides)Expand
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Insulin resistance in the control of body fat distribution: a new hypothesis.
Obesity causes insulin resistance, which is a prime etiological factor for type 2 diabetes, dyslipidemia, and cardiovascular disease. However, insulin resistance may be a normal physiologicalExpand
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Plasma fatty acid levels in South African interethnic male high school pupils at different ultimate risks of coronary heart disease.
While coronary heart disease (CHD) is responsible for about a quarter of deaths in South African white, coloured and Indian populations, the rate is very low in the black population. Dietary riskExpand
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Steatosis in South African women: How much and why?
Background Globally, steatosis is the commonest type of liver pathology and is closely associated with obesity and the metabolic syndrome. Obesity is common in urban African females but no data isExpand
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The in vitro effect of ridogrel on platelet function in normocholesterolaemic and familial hypercholesterolaemic type IIa subjects.
Platelets from familial hypercholesterolaemia type IIa patients are hyperreactive and produce increased amounts of thromboxane A2. These modifications of platelet function may play an important roleExpand
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The prevalence of the platelet glycoprotein IIIa Pl(A1/A2) polymorphism in three South African ethnic groups and its effect on platelet function.
INTRODUCTION In South Africa coronary artery disease (CAD) is less common in African than Indian or white subjects. Although the association between CAD and metabolic factors have been wellExpand
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Physicians' responses to diagnostic test guidelines.
Internists (IM), subspecialty internists (SS), and family practitioners (FP) were surveyed regarding their opinions of ten of the Blue Cross Blue Shield Association/American College of PhysiciansExpand
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