• Publications
  • Influence
Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats
Administration of turmeric or curcumin to diabetic rats reduced the blood sugar, Hb and glycosylatedhemoglobin levels significantly andcurcumin was more effective in attenuating diabetes Mellitus related changes than turmeric. Expand
What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
The published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources, and animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials. Expand
Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer.
  • V. Manju, N. Nalini
  • Chemistry, Medicine
  • Clinica chimica acta; international journal of…
  • 1 August 2005
Ginger supplementation suppresses colon carcinogenesis in the presence of the procarcinogen DMH and significantly reduced circulating lipid peroxidation and significantly enhanced the enzymic and non-enzymic antioxidants as compared to unsupplemented DMH-treated rats. Expand
Protective effect of quercetin on nicotine-induced prooxidant and antioxidant imbalance and DNA damage in Wistar rats.
The data suggest that QN exerts its protective effect by modulating the extent of lipid peroxidation and augmenting antioxidant defense system and thus protects the DNA in experimental animals. Expand
Dietary supplementation of resveratrol suppresses colonic tumour incidence in 1,2-dimethylhydrazine-treated rats by modulating biotransforming enzymes and aberrant crypt foci development
The inhibitory effect of resveratrol is demonstrated on DMH-induced colon carcinogenesis in rats by modulating the development of aberrant crypt foci and the activities of bacterial enzymes. Expand
Evidence of oxidative stress in the circulation of ovarian cancer patients.
The low levels of SOD, CAT, vitamin C and vitamin E in the plasma of ovarian cancer patients may be due to their increased utilization to scavenge lipid peroxides as well as their sequestration by tumor cells. Expand
Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon
It is indicated that resveratrol effectively inhibits DMH-induced ACF and colonic tumor development and modulation of lipid peroxidation markers and antioxidants status, which were paralleled with ACF suppression, as compared toDMH-alone treated rats. Expand
Effect of coconut cake on the bacterial enzyme activity in 1,2-dimethyl hydrazine induced colon cancer.
Coconut cake has a protective effect against DMH induced colon cancer by virtue of its ability to lower the activities of the microbial enzymes beta-glucuronidase and mucinase. Expand
Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress
The data indicate that supplementation with black pepper or the active principle of black pepper, piperine, can reduce high-fat diet induced oxidative stress to the cells. Expand
Dietary d-limonene alleviates insulin resistance and oxidative stress–induced liver injury in high-fat diet and L-NAME-treated rats
Dietary supplementation with d-limonene reversed the HFD and L-NAME-induced changes and restored pathological alteration of liver and pancreas and provides new insights into the therapeutic approach of d- Limonene against the development of the metabolic syndrome associated with NAFLD. Expand