• Publications
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A Metagenomic Survey of Microbes in Honey Bee Colony Collapse Disorder
The observation that irradiated combs from affected colonies can be repopulated with naive bees suggests that infection may contribute to colony collapse disorder (CCD). Expand
Genomics and evolution of heritable bacterial symbionts.
Insect heritable symbionts provide some of the extremes of cellular genomes, including the smallest and the fastest evolving, raising new questions about the limits of evolution of life. Expand
The gut microbiota of insects - diversity in structure and function.
Gut bacteria of other insects have also been shown to contribute to nutrition, protection from parasites and pathogens, modulation of immune responses, and communication, and the extent of these roles is still unclear and awaits further studies. Expand
Facultative bacterial symbionts in aphids confer resistance to parasitic wasps
Investigation of aphids for vulnerability of the aphid host to a hymenopteran parasitoid, Aphidius ervi, shows that infection confers resistance to parasitoids attack by causing high mortality of developing Parasitoid larvae. Expand
Extreme genome reduction in symbiotic bacteria
Since 2006, numerous cases of bacterial symbionts with extraordinarily small genomes have been reported, pointing to highly degenerate genomes that retain only the most essential functions, often including a considerable fraction of genes that serve the hosts. Expand
The Evolutionary Maintenance of Alternative Phenotypes
  • N. Moran
  • Biology
  • The American Naturalist
  • 1 May 1992
Polyphenism may be restricted to circumstances in which the developmental switch occurs during very early development, and the abundance of seasonal polyphenisms in multivoltine organisms suggests that where environments are favorable, developmental systems are often flexible enough for the establishment of simple polyphenism. Expand
Facultative symbionts in aphids and the horizontal transfer of ecologically important traits.
Experiments on pea aphids have demonstrated that facultative symbionts protect against entomopathogenic fungi and parasitoid wasps, ameliorate the detrimental effects of heat, and influence host plant suitability. Expand
A simple and distinctive microbiota associated with honey bees and bumble bees
It is found that most bee species lack phylotypes that are the same or similar to those typical of A. mellifera, rejecting the hypothesis that this dietary transition was symbiont‐dependent and potentially key to the maintenance of a more consistent gut microbiota. Expand
Accelerated evolution and Muller's rachet in endosymbiotic bacteria.
  • N. Moran
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2 April 1996
Polypeptides for all Buchnera genes analyzed have accumulated amino acids with codon families rich in A+T, supporting the hypothesis that substitutions are deleterious in terms of polypeptide function, and the observation that the speedup is concentrated at nonsynonymous sites is contradicted. Expand
Deletional bias and the evolution of bacterial genomes.
The evidence showing that deletional bias is a major force that shapes bacterial genomes is discussed, in which dramatic reductions in genome size can result not from selection to lose DNA, but from decreased selection to maintain gene functionality. Expand