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In vitro screening of traditional South African malaria remedies against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum.
Three hundred extracts were prepared from plants traditionally used in South Africa to treat malaria and screened in vitro for activity against Trypanosoma brucei rhodesiense, Trypanosoma cruzi,Expand
Identification of compounds from the plant species Alepidea amatymbica active against HIV
As Alepidea amatymbica is commonly used and accepted as medicinal plant in South Africa for various indications, the scientific basis of its anecdotally described, putative anti-HIV properties wasExpand
Antioxidant and acetylcholinesterase inhibitory activity of selected southern African medicinal plants
Alzheimer's disease (AD) is the most common type of dementia in the aging population. Enhancement of acetylcholine levels in the brain is one means of treating the disease. However, the drugsExpand
The antimicrobial, antioxidative, anti-inflammatory activity and cytotoxicity of different fractions of four South African Bauhinia species used traditionally to treat diarrhoea.
ETHNOPHARMACOLOGICAL IMPORTANCE Many Bauhinia species, including those indigenous to South Africa, are used in traditional medicine across the world for treating ailments such as gastrointestinalExpand
Medicinal plants with cholinesterase inhibitory activity: A Review
Alzheimer’s disease (AD), a common neurodegenerative disease, is characterized by low levels in the brain of the neurotransmitter, acetylcholine (ACh). Clinical treatment of this disease isExpand
Antiprotozoal screening of 60 South African plants, and the identification of the antitrypanosomal germacranolides schkuhrin I and II.
Two hundred and seven extracts were prepared from sixty plants from South Africa and screened for in vitro activity against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, andExpand
The chemical investigation of the Amaryllidaceae and Hyacinthaceae.
This work is an account of investigations into the chemistry of members of the Amaryllidaceae and Hyacinthaceae families. The plants of the family Amaryllidaceae are a large group comprising overExpand
Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)
Abstract In South Africa, Salvia repens is used traditionally to treat sores, stomach ache and diarrhoea. The high performance liquid chromatography (HPLC)-based activity profiling of S. repens wholeExpand
Rapid Identification of Bioactive Compounds Reducing the Production of Amyloid β-Peptide (Aβ) from South African Plants Using an Automated HPLC/SPE/HPLC Coupling System
Abstract of many novel therapeutic agents (John, 2009). However, the classical bioactivity-guided fractionation for the purifi cation and identi fi cation of biologically active compounds from plantsExpand
Cytotoxic, antimicrobial, antioxidant, antilipoxygenase activities and phenolic composition of Ozoroa and Searsia species (Anacardiaceae) used in South African traditional medicine for treating
Abstract The safety and effectiveness of many of the medicinal plants used in traditional medicine by rural people with little or no access to allopathic drugs is yet to be evaluated. With this inExpand