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Trypanosoma cruzi Infection at the Maternal-Fetal Interface: Implications of Parasite Load in the Congenital Transmission and Challenges in the Diagnosis of Infected Newborns
Trypanosoma cruzi is the protozoan unicellular parasite that causes Chagas disease. It can be transmitted from infected mothers to their babies via the connatal route, thus being able to perpetuateExpand
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A homolog of cyclophilin D is expressed in Trypanosoma cruzi and is involved in the oxidative stress–damage response
Mitochondria have an important role in energy production, homeostasis and cell death. The opening of the mitochondrial permeability transition pore (mPTP) is considered one of the key events inExpand
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Oxidative stress damage in the protozoan parasite Trypanosoma cruzi is inhibited by Cyclosporin A.
Cyclosporin A (CsA) specifically inhibits the mitochondrial permeability transition pore (mPTP). Opening of the mPTP, which is triggered by high levels of matrix [Ca2+] and/or oxidative stress, leadsExpand
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Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
Mitochondrial permeability transition in protozoan parasites: what we learned from Trypanosoma cruzi
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A Functional Analysis of the Cyclophilin Repertoire in the Protozoan Parasite Trypanosoma Cruzi
Trypanosoma cruzi is the etiological agent of Chagas disease. It affects eight million people worldwide and can be spread by several routes, such as vectorborne transmission in endemic areas andExpand
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Improved Immuno-Detection of a Low-Abundance Cyclophilin Allows the Confirmation of its Expression in a Protozoan Parasite
Protein samples can be challenging to analyze due to the presence of high-abundance proteins masking lowabundance proteins of interest, such as biomarkers and novel physiological mediators.Expand
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Circulating cytokine and chemokine profiles of Trypanosoma cruzi-infected women during pregnancy and its association with congenital transmission.
BACKGROUND Trypanosoma cruzi, the causative agent of Chagas disease, can be transmitted to the offspring of infected women, which constitutes an epidemiologically significant parasite transmissionExpand
Trypanosoma cruzi infection in Cyclophilin D deficient mice.
Trypanosoma cruzi is the causative agent of Chagas disease, which is endemic in Latin America and around the world through mother to child transmission. The heart is the organ most frequentlyExpand
Conectándonos con las Ciencias y las Matemáticas
Presentamos el analisis de experiencias del ano de ejecucion de un PEU dirigido a favorecer la efectiva utilizacion pedagogica de las netbooks entregadas a escuelas secundarias de Quilmes, por elExpand