N. Mello

Publications406
h-index67
Citations15,115
Highly Influential Citations533
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Playing Linear Number Board Games — But Not Circular Ones — Improves Low-Income Preschoolers ’ Numerical Understanding
concepts: The case of natural number. Journal of Experimental Psychology: General, 137, 22–38. Dehaene, S. (1997). The number sense: How the mind creates mathematics. New York: Oxford University…
Modification of cocaine self-administration by buspirone (buspar®): potential involvement of D3 and D4 dopamine receptors.
TLDR
The present research examined the functional effects of buspirone on D3 and D4 receptors and its ability to modify the reinforcing effects of i.v. cocaine in a behaviourally selective manner, supporting the further evaluation of busPirone as a candidate medication for the management of cocaine addiction.
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Age-related Reduction in Functional MRI Response to Photic Stimulation
TLDR
It is found that the amplitude of response in elderly subjects was significantly decreased compared to younger subjects, suggesting a reduction in functional activation or an age-related alteration in the coupling of blood oxygenation to focal activation.
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Preclinical Evaluation of Pharmacotherapies for Treatment of Cocaine and Opioid Abuse Using Drug Self-Administration Procedures
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Hyponatremia in marathon runners due to inappropriate arginine vasopressin secretion.
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Buprenorphine suppresses heroin use by heroin addicts.
TLDR
Buprenorphine should be a safe and effective new pharmacotherapy for heroin dependence and indicated that it was preferable to methadone or naltrexone.
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Effects of kappa opioids on cocaine self-administration by rhesus monkeys.
TLDR
It is shown that chronic administration of EKC and U50,588 produce a dose-dependent, kappa receptor-mediated and often sustained decrease in cocaine self-administration, which may complicate their use as treatments for cocaine dependence.
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Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys.
  • N. Mello, S. Negus
  • Biology, Medicine
    The Journal of pharmacology and experimental…
  • 1 August 1998
TLDR
It is suggested that kappa opioid agonists may be a useful approach to the development of new pharmacological treatments for cocaine dependence and undesirable side effects may limit their clinical usefulness.
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Cocaine Pharmacokinetics in Men and in Women During the Follicular and Luteal Phases of the Menstrual Cycle
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Nicotine-like behavioral effects of the minor tobacco alkaloids nornicotine, anabasine, and anatabine in male rodents.
TLDR
Results suggest that the minor tobacco alkaloids may substitute for the subjective effects of nicotine and attenuate withdrawal and craving without the abuse liability of nicotine.
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