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Caregiver Burden Associated with Behavioral and Psychological Symptoms of Dementia in Elderly People in the Local Community
Background: Despite many studies about the association between caregiver burden and behavioral and psychological symptoms of dementia (BPSD), there have been no population-based studies to evaluateExpand
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Dynamic and Functional Assembly of the AAA Peroxins, Pex1p and Pex6p, and Their Membrane Receptor Pex26p*
Two AAA peroxins, Pex1p and Pex6p, are encoded by PEX1 and PEX6, the causal genes for peroxisome biogenesis disorders of complementation group 1 (CG1) and CG4, respectively. PEX26 responsible forExpand
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Dopaminergic D1 and D2 Receptors Are Essential for the Arousal Effect of Modafinil
Modafinil is a wake-promoting compound with low abuse potential used in the treatment of narcolepsy. Although the compound is reported to affect multiple neurotransmitter systems such asExpand
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The pathogenic peroxin Pex26p recruits the Pex1p–Pex6p AAA ATPase complexes to peroxisomes
Peroxisomes are ubiquitous organelles with a single membrane that contain over 50 different enzymes that catalyse various metabolic pathways, including β-oxidation and lipid synthesis. PeroxisomeExpand
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AAA Peroxins and Their Recruiter Pex26p Modulate the Interactions of Peroxins Involved in Peroxisomal Protein Import*
Background: Pex26p and AAA peroxins are required for the peroxisome biogenesis. Results: Pex26p directly binds to Pex14p and acts as a scaffold protein to specify the molecular target of AAAExpand
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Frequency and Clinical Characteristics of Early-Onset Dementia in Consecutive Patients in a Memory Clinic
Aims: To investigate the frequency, rate of causes of dementia, and clinical characteristics of early-onset dementia in consecutive patients of a memory clinic. Methods: A total of 668 consecutiveExpand
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Comparison of one-year outcomes between 23- and 20-gauge vitrectomy for preretinal membrane.
PURPOSE To compare the outcomes of transconjunctival sutureless 23-gauge vitrectomy and conventional 20-gauge vitrectomy 1 year after removal of preretinal membrane. DESIGN Retrospective,Expand
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An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue
The altered form of the high-mobility group A2 (HMGA2) gene is somehow related to the generation of human benign and malignant tumours of mesenchymal origin. However, only a few data on theExpand
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Amino Acid Changes in Hemagglutinin Contribute to the Replication of Oseltamivir-Resistant H1N1 Influenza Viruses
ABSTRACT Oseltamivir-resistant H1N1 influenza viruses emerged in 2007 to 2008 and have subsequently circulated widely. However, prior to 2007 to 2008, viruses possessing the neuraminidase (NA) H274YExpand
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A longitudinal study regarding conversion from mild memory impairment to dementia in a Japanese community
To estimate the rate that subjects with Mild Memory Impairment /Not Dementia (MMI/ND) shifted to dementia in a population‐based cohort and to establish simple diagnostic methods for identification ofExpand
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