• Publications
  • Influence
Relaxometry of brain: Why white matter appears bright in MRI
The remarkable success of magnetic resonance imaging of adult brain relates to the unusually large ratio of the longitudinal relaxation rates 1 / T1 of white and gray matter, ∼2:1 at physiologicalExpand
  • 252
  • 13
Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects.
OBJECTIVE Endocannabinoids (ECs) control metabolism via cannabinoid receptors type 1 (CB1). Their plasma levels are elevated in overweight type 2 diabetes (T2D) and in obese patients, and decreaseExpand
  • 103
  • 8
  • PDF
Nonalcoholic fatty liver disease: detection of elevated nicotinamide adenine dinucleotide phosphate with in vivo 3.0-T 31P MR spectroscopy with proton decoupling.
PURPOSE To determine if 3.0-T proton-decoupled phosphorus 31 ((31)P) magnetic resonance (MR) spectroscopy can be used to differentiate between stages of nonalcoholic fatty liver disease (NAFLD) byExpand
  • 44
  • 6
Increased coagulation factor VIII, IX, XI and XII activities in non‐alcoholic fatty liver disease
Background and aims: Obesity and the metabolic syndrome are established risk factors of venous thromboembolism. As most coagulation factors are produced exclusively by the liver and non‐alcoholicExpand
  • 65
  • 5
Brain metabolic alterations in adolescents and young adults with fetal alcohol spectrum disorders.
BACKGROUND Prenatal alcohol exposure affects brain structure and function. This study examined brain metabolism using magnetic resonance spectroscopy (MRS) and searched for regions of specificExpand
  • 67
  • 5
Proton magnetic resonance spectroscopic imaging in progressive supranuclear palsy, Parkinson's disease and corticobasal degeneration.
We used proton magnetic resonance spectroscopic imaging (1H-MRSI) to assess the in vivo cortical and subcortical neuronal involvement in progressive supranuclear palsy, Parkinson's disease andExpand
  • 134
  • 4
  • PDF
Ectopic Fat Depots and Left Ventricular Function in Nondiabetic Men With Nonalcoholic Fatty Liver Disease
Background—Nonalcoholic fatty liver disease has emerged as a novel cardiovascular risk factor. The aim of the study was to assess the effect of different ectopic fat depots on left ventricular (LV)Expand
  • 63
  • 4
Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain
Aims/hypothesisThe aim of the study was to assess the effect of hyperglycaemia on regional concentrations of glucose and other substrates within the brain in non-diabetic individuals and in patientsExpand
  • 39
  • 4
Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
OBJECTIVE Nonalcoholic fatty liver disease (i.e., increased intrahepatic triglyceride [IHTG] content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue lipolysis and hepaticExpand
  • 104
  • 3
  • PDF
Low-grade gliomas and focal cortical developmental malformations: differentiation with proton MR spectroscopy.
PURPOSE To assess proton magnetic resonance (MR) spectroscopy in differentiating between low-grade gliomas and focal cortical developmental malformations (FCDMs). MATERIALS AND METHODS EighteenExpand
  • 83
  • 3