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Relaxometry of brain: Why white matter appears bright in MRI
- S. Koenig, R. D. Brown, M. Spiller, N. Lundbom
- Chemistry, Medicine
- Magnetic resonance in medicine
- 1 June 1990
The remarkable success of magnetic resonance imaging of adult brain relates to the unusually large ratio of the longitudinal relaxation rates 1 / T1 of white and gray matter, ∼2:1 at physiological… Expand
Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects.
- V. Di Marzo, A. Verrijken, +9 authors M. Taskinen
- European journal of endocrinology
- 1 November 2009
OBJECTIVE Endocannabinoids (ECs) control metabolism via cannabinoid receptors type 1 (CB1). Their plasma levels are elevated in overweight type 2 diabetes (T2D) and in obese patients, and decrease… Expand
Nonalcoholic fatty liver disease: detection of elevated nicotinamide adenine dinucleotide phosphate with in vivo 3.0-T 31P MR spectroscopy with proton decoupling.
PURPOSE To determine if 3.0-T proton-decoupled phosphorus 31 ((31)P) magnetic resonance (MR) spectroscopy can be used to differentiate between stages of nonalcoholic fatty liver disease (NAFLD) by… Expand
Increased coagulation factor VIII, IX, XI and XII activities in non‐alcoholic fatty liver disease
- A. Kotronen, L. Joutsi-Korhonen, +7 authors H. Yki–Järvinen
- Liver international : official journal of the…
- 1 February 2011
Background and aims: Obesity and the metabolic syndrome are established risk factors of venous thromboembolism. As most coagulation factors are produced exclusively by the liver and non‐alcoholic… Expand
Brain metabolic alterations in adolescents and young adults with fetal alcohol spectrum disorders.
- Å. Fagerlund, S. Heikkinen, +5 authors N. Lundbom
- Alcoholism, clinical and experimental research
- 1 December 2006
BACKGROUND Prenatal alcohol exposure affects brain structure and function. This study examined brain metabolism using magnetic resonance spectroscopy (MRS) and searched for regions of specific… Expand
Proton magnetic resonance spectroscopic imaging in progressive supranuclear palsy, Parkinson's disease and corticobasal degeneration.
- G. Tedeschi, I. Litvan, +4 authors M. Hallett
- Psychology, Medicine
- Brain : a journal of neurology
- 1 September 1997
We used proton magnetic resonance spectroscopic imaging (1H-MRSI) to assess the in vivo cortical and subcortical neuronal involvement in progressive supranuclear palsy, Parkinson's disease and… Expand
Ectopic Fat Depots and Left Ventricular Function in Nondiabetic Men With Nonalcoholic Fatty Liver Disease
- M. Granér, K. Nyman, +7 authors M. Taskinen
- Circulation. Cardiovascular imaging
- 30 December 2014
Background—Nonalcoholic fatty liver disease has emerged as a novel cardiovascular risk factor. The aim of the study was to assess the effect of different ectopic fat depots on left ventricular (LV)… Expand
Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain
- O. Heikkilä, N. Lundbom, M. Timonen, P. Groop, S. Heikkinen, S. Mäkimattila
- 1 March 2009
Aims/hypothesisThe aim of the study was to assess the effect of hyperglycaemia on regional concentrations of glucose and other substrates within the brain in non-diabetic individuals and in patients… Expand
Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
OBJECTIVE Nonalcoholic fatty liver disease (i.e., increased intrahepatic triglyceride [IHTG] content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue lipolysis and hepatic… Expand
Low-grade gliomas and focal cortical developmental malformations: differentiation with proton MR spectroscopy.
PURPOSE To assess proton magnetic resonance (MR) spectroscopy in differentiating between low-grade gliomas and focal cortical developmental malformations (FCDMs). MATERIALS AND METHODS Eighteen… Expand