• Publications
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Risk Factors for ERCP-Related Complications: A Prospective Multicenter Study
  • P. Wang, Z. Li, +13 authors F. Zhi
  • Medicine
  • The American Journal of Gastroenterology
  • 1 January 2009
TLDR
Patient- related factors are as important as procedure-related factors in determining high-risk predictors for post-ERCP overall complications and pancreatitis, however, the risk factors for asymptomatic hyperamylasemia may be mostly procedure related. Expand
A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition
TLDR
A better understanding of the regulatory mechanisms related to the EMT can provide a theoretical basis for the early prediction of tumor progression as well as targeted therapy. Expand
All‐trans retinoic acid down‐regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis
TLDR
RA down‐regulates colon inflammatory responses in patients with IBD in vitro and in murine colitis in vivo, representing a potential therapeutic approach in IBD treatment. Expand
Fourth Chinese National Consensus Report on the management of Helicobacter pylori infection
TLDR
A Delphi method was adopted to develop the consensus of relevant statements and the initial statements were discussed face to face and revised in the conference item by item on 16 December 2016. Expand
Primary Antibiotic Resistance of Helicobacter pylori in China
TLDR
In China, the prevalence of H. pylori primary resistance to clarithromycin, metronidazole, and levofloxacin was high and increased over time, whereas the resistance rates to amoxicillin, tetracycline, and furazolidone were low and stable over time. Expand
Extracellular ATP mediates inflammatory responses in colitis via P2 × 7 receptor signaling
TLDR
Data suggest extracellular ATP participates in regulation of inflammatory responses of experimental colitis, through P2 × 7 receptor and inflammasome and NFκB signaling, which provides potential alternatives to the current clinical approaches to suppress extrace cellular ATP-mediated immune responsiveness. Expand
All-trans retinoic acid ameliorates trinitrobenzene sulfonic acid-induced colitis by shifting Th1 to Th2 profile.
  • A. Bai, N. Lu, +6 authors Y. Guo
  • Chemistry, Medicine
  • Journal of interferon & cytokine research : the…
  • 21 September 2010
TLDR
By shifting Th1 to Th2 profile in inflamed mucosa, all-trans retinoic acid down-regulates inflammatory response and ameliorates acute TNBS-induced colitis, which suggests the ligand of RAR-alpha-based pharmaceutical strategies for managing inflammatory bowel disease. Expand
Modulation of inflammatory response via α2‐adrenoceptor blockade in acute murine colitis
TLDR
The data show a critical role of catecholamines via α2‐adrenoreceptors in the progress of acute colitis, and suggest that use of the α2-adrenoceptor antagonist represents a novel therapeutic approach for the management of colitis. Expand
Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis
TLDR
It is shown that parasite infection acts through host type 2 immunity to reduce intestinal SFB and expression of IL-17, providing an example of a microbiota-dependent immune modulation by parasites. Expand
Clinical Use and Mechanisms of Infliximab Treatment on Inflammatory Bowel Disease: A Recent Update
TLDR
The clinical use and recently advanced biological action of infliximab on IBD, a monoclonal antibody of tumor necrosis factor, has emerged as an efficient treatment with many clinical benefits such as quick disease activity reduction and IBD patient life quality improvement. Expand
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