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Comparisons of mutation induction by six monocyclic aromatic amines in Salmonella typhimurium tester strains TA97, TA1537, and TA1538.
The mutagenicity of six monocyclic aromatic amines was investigated in Salmonella typhimurium strains TA97, TA1537, and TA1538 in the presence of two different amounts of Aroclor 1254-induced S9 preparations with the same relationship between chemical structure and mutagenic activity observed. Expand
Mutagenicity of structurally related aromatic amines in the Salmonella/mammalian microsome test with various S-9 fractions.
S-9 fractions from rat liver induced with Aroclor 1254 or with a combination of phenobarbital and 5,6-benzoflavone activated both DAA and DAPB, DAA being by far the more mutagenic of the two, and the mutagenicity ranking of the aromatic amines was DAA greater than D APB greater thanDABB. Expand