N. Leonard

Publications543
h-index50
Citations10,988
Highly Influential Citations63
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Synthetic spectroscopic models related to coenzymes and base pairs. V. Emission properties of NADH. Studies of fluorescence lifetimes and quantum efficiencies of NADH, AcPyADH, [reduced…
Etheno-substituted nucleotides and coenzymes: fluorescence and biological activity.
  • N. Leonard
  • Biology, Medicine
  • CRC critical reviews in biochemistry
  • 1984
TLDR
The binding of e-substituted nucleotides or polynucleotides to proteins has been determined for F- and G-actin, heavy meromyosin, tobacco mosaic virus protein, gene 32 protein of bacteriophage T4, and chloroplast... Expand
Fluorescent modification of adenosine-containing coenzymes. Biological activities and spectroscopic properties.
1,N2-ethenoguanine and N2,3-ethenoguanine. Synthesis and comparison of the electronic spectral properties of these linear and angular triheterocycles related to the Y bases.
Synthetic spectroscopic models related to coenzymes and base pairs. II. Evidence for intramolecular base-base interactions in dinucleotide analog.
Cytokinins: Structure/activity relationships☆
Abstract Sixty-nine compounds, mostly purine derivatives and closely related substances, were tested for promotion of growth and regulation of organ formation in the tobacco bioassay to determine… Expand
Adenosine cyclic 3',5'-monophosphate dependent protein kinase: a new fluorescence displacement titration technique for characterizing the nucleotide binding site on the catalytic subunit.
TLDR
It is found that modifications of the adenine moiety reduce nucleotide affinity for the enzyme, and was most pronounced with modifications at position 6 of the base. Expand
Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway.
TLDR
A new energy requirement in the purine biosynthetic pathway has been established and the gene products of the purE and purK genes thought to be responsible for this activity have been overexpressed and the proteins purified to homogeneity. Expand
Specificity of the 1-methyladenine receptors in starfish oocytes: synthesis and properties of some 1,8-disubstituted adenines, 1,6-dimethyl-1H-purine, and of the 1-(azidobenzyl)adenines
A selective synthesis of 1,6-dimethylpurine (16) and the preparations of the 1-(azidobenzyl)adenines (11)–(13), 8-azido-1-benzyladenine (10), and 1-methyladenine derivatives (2)–(9) with various… Expand
Isolation of cis-Zeatin from Corynebacterium fascians Cultures.
TLDR
Three cytokinin-active constituents have been isolated from the culture medium of Corynebacterium fascians, a plant pathogen causing fasciation and one constituent is now identified as cis-zeatin, which represents the first unequivocal demonstration of the production of a zeatin isomer by a bacterial species. Expand
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