Etheno-substituted nucleotides and coenzymes: fluorescence and biological activity.
- N. Leonard
- Biology, ChemistryCRC Critical Reviews in Biochemistry
- 1984
The binding of e-substituted nucleotides or polynucleotides to proteins has been determined for F- and G-actin, heavy meromyosin, tobacco mosaic virus protein, gene 32 protein of bacteriophage T4, and chloroplast...
Synthetic spectroscopic models related to coenzymes and base pairs. V. Emission properties of NADH. Studies of fluorescence lifetimes and quantum efficiencies of NADH, AcPyADH, [reduced…
- T. G. Scott, R. Spencer, N. Leonard, G. Weber
- Chemistry
- 1 February 1970
Synthesis of modified nucleoside 3',5'-bisphosphates and their incorporation into oligoribonucleotides with T4 RNA ligase.
- J. Barrio, M. C. Barrio, N. Leonard, T. England, O. Uhlenbeck
- Chemistry, BiologyBiochemistry
- 30 May 1978
A simple procedure is described to prepare nucleoside 3'(2'),5'-bisphosphates from the corresponding nucleosides with the use of pyrophosphoryl chloride. This method is rapid, gives nearly…
Fluorescent modification of adenosine-containing coenzymes. Biological activities and spectroscopic properties.
- J. Secrist, J. Barrio, N. Leonard, G. Weber
- ChemistryBiochemistry
- 12 September 1972
1,N2-ethenoguanine and N2,3-ethenoguanine. Synthesis and comparison of the electronic spectral properties of these linear and angular triheterocycles related to the Y bases.
- P. D. Sattsangi, N. Leonard, C. Frihart
- ChemistryJournal of Organic Chemistry
- 30 September 1977
Cytokinins: Structure/activity relationships☆
- F. Skoog, H. Q. Hamzi, R. Loeppky
- Chemistry
- 1 September 1967
Synthetic spectroscopic models related to coenzymes and base pairs. II. Evidence for intramolecular base-base interactions in dinucleotide analog.
- D. T. Browne, J. Eisinger, N. Leonard
- ChemistryJournal of the American Chemical Society
- 18 December 1968
Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway.
- E. Meyer, N. Leonard, B. Bhat, J. Stubbe, J. Smith
- BiologyBiochemistry
- 2 June 1992
A new energy requirement in the purine biosynthetic pathway has been established and the gene products of the purE and purK genes thought to be responsible for this activity have been overexpressed and the proteins purified to homogeneity.
Azido auxins: quantitative binding data in maize.
- A. Jones, L. Melhado, T. Ho, N. Leonard
- Biology, ChemistryPlant Physiology
- 1 February 1984
It is found that IAA or NAA, included with this 5-N(3)IAA pretreatment, can protect the sites from blockage, whereas benzoic acid and tryptophan are unable to protect the site, indicating that 5- naphthalene-1-acetic acid specifically labels the auxin sites.
Specificity of the 1-methyladenine receptors in starfish oocytes: synthesis and properties of some 1,8-disubstituted adenines, 1,6-dimethyl-1H-purine, and of the 1-(azidobenzyl)adenines
- R. Mornet, N. Leonard, J. B. Theiler, M. Dorée
- Chemistry, Biology
- 21 August 1984
The low level of activity of the 8-azido derivatives of 1-methyl- and 1-benzyl-adenines, probably due to blocking of the N-7, N-9 region and reduction of the pKa, value, precludes their use as photoaffinity labelling reagents for the receptors of 1 -methyladenine.
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