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Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study
- N. Kuppermann, J. Holmes, P. Dayan, J. Hoyle, For the Pediatric Emergency Care Applied Research Network
- The Lancet
- 3 October 2009
BACKGROUND CT imaging of head-injured children has risks of radiation-induced malignancy. Our aim was to identify children at very low risk of clinically-important traumatic brain injuries (ciTBI)… Expand
Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.
- N. Glaser, P. Barnett, +8 authors N. Kuppermann
- The New England journal of medicine
- 25 January 2001
BACKGROUND Cerebral edema is an uncommon but devastating complication of diabetic ketoacidosis in children. Risk factors for this complication have not been clearly defined. METHODS In this… Expand
Identification of children with intra-abdominal injuries after blunt trauma.
STUDY OBJECTIVE We sought to determine the utility of laboratory testing after adjusting for physical examination findings in the identification of children with intra-abdominal injuries after blunt… Expand
A decision rule for identifying children at low risk for brain injuries after blunt head trauma.
- M. J. Palchak, J. Holmes, +7 authors N. Kuppermann
- Annals of emergency medicine
- 1 October 2003
STUDY OBJECTIVE Computed tomography (CT) is frequently used in evaluating children with blunt head trauma. Routine use of CT, however, has disadvantages. Therefore, we sought to derive a decision… Expand
Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections.
BACKGROUND The evaluation of young febrile infants is controversial, in part because it is unclear whether clinical evidence of a viral infection significantly reduces the risk of serious bacterial… Expand
Mechanism of cerebral edema in children with diabetic ketoacidosis.
- N. Glaser, S. Wootton-Gorges, +6 authors N. Kuppermann
- The Journal of pediatrics
- 1 August 2004
OBJECTIVES Cerebral edema during diabetic ketoacidosis (DKA) has been attributed to osmotic cellular swelling during treatment. We evaluated cerebral water distribution and cerebral perfusion during… Expand
Risks for bacteremia and urinary tract infections in young febrile children with bronchiolitis.
- N. Kuppermann, D. Bank, E. Walton, M. Senac, I. McCaslin
- Archives of pediatrics & adolescent medicine
- 1 December 1997
OBJECTIVE To compare the risks for bacteremia and urinary tract injections (UTI) in young febrile children with and without bronchiolitis. DESIGN A prospective cohort study. SETTING The emergency… Expand
Performance of the pediatric glasgow coma scale in children with blunt head trauma.
- J. Holmes, M. J. Palchak, T. Macfarlane, N. Kuppermann
- Academic emergency medicine : official journal of…
- 1 September 2005
OBJECTIVES To compare the accuracy of a pediatric Glasgow Coma Scale (GCS) score in preverbal children with blunt head trauma with the standard GCS score in older children. METHODS The authors… Expand
Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era.
CONTEXT Children with meningitis are routinely admitted to the hospital and administered broad-spectrum antibiotics pending culture results because distinguishing bacterial meningitis from aseptic… Expand
Effect of Antibiotic Pretreatment on Cerebrospinal Fluid Profiles of Children With Bacterial Meningitis
OBJECTIVE. The goal of this study was to evaluate the effect of antibiotic administration before lumbar puncture on cerebrospinal fluid profiles in children with bacterial meningitis. METHODS. We… Expand