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Sperm-associated antigen 9 is associated with tumor growth, migration, and invasion in renal cell carcinoma.
TLDR
SPAG9 expression is associated with clinicopathologic features of tumors, suggesting that SPAG9 could contribute to the early spread of cancer and thus could serve as a novel target for early detection and treatment of RCC. Expand
Chloroform extract of Carica papaya seeds induces long-term reversible azoospermia in langur monkey.
TLDR
Carica papaya seed extract may selectively act on the developing germ cells, possibly mediated via Sertoli cells, leading to azoospermia. Expand
Toxicological investigations on the methanol sub-fraction of the seeds of Carica papaya as a male contraceptive in albino rats.
TLDR
The preliminary results suggest the test substance may be a safe approach to male anti-fertility, and sperm density showed a significant decrease in all 28- and 90-day repeated dose treated animals. Expand
Sperm‐associated antigen 9 is a biomarker for early cervical carcinoma
TLDR
Evaluated the clinical utility of SPAG9 expression and humoral immune response in cervical carcinomas and suggested an association with cancer testis antigen sperm‐associated antigen 9 in ovarian carcinomas. Expand
Sterility due to inhibition of sperm motility by oral administration of benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rats.
TLDR
The results suggest that the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya exerts antifertility effects in rats without adverse toxicity and that the effects may be directly rendered on the spermatozoa. Expand
The effect of chronically administered cannabis extract on the testicular function of mice.
TLDR
Daily administration of cannabis extract produced a complete arrest of spermatogenesis in mice and regression of Leydig cell tissue and of accessory sex glands was conspicuous. Expand
Human sperm immobilization effect of Carica papaya seed extracts: an in vitro study.
TLDR
The results reveal spermicidal activity in vitro of the seed extracts of Carica papaya, which showed antispermatogenic/sperm immobilization properties in animal models, could cause human sperm immobilization in vitro. Expand
Antifertility effects of aqueous extract of Carica papaya seeds in male rats.
TLDR
The data revealed that reversible sterility could be induced in male rats by papaya seeds aqueous extract treatment without adverse effects on libido and toxicological profile. Expand
Sperm motility inhibitory effect of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in langur monkey, Presbytis entellus entellus.
TLDR
The results suggest that the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya shows contraceptive efficacy without adverse toxicity, mediated through inhibition of sperm motility. Expand
Safety evaluation of long-term vas occlusion with styrene maleic anhydride and its non-invasive reversal on accessory reproductive organs in langurs.
TLDR
Although fructose, acid phosphatase (ACP) and zinc in the seminal plasma showed a significant reduction following vas occlusion, it could not be related to the morphology of seminal vesicle and prostate. Expand
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