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Trofosides A and B and other cytostatic steroid-derived compounds from the far east starfish Trofodiscus über
Of three compounds highly toxic in embryos and sea-urchin sperm cells, the polyol with a sulfo group in the steroid core was the most active; two glycosides with monosaccharide chains located at C3 and C24 atoms were less toxic.
Application of different test systems and biochemical indicators for environmental monitoring of the Troitsa Bay, Sea of Japan
The DNase express test system and the SF-bioassay (sea urchin sperm fertilization bioassay) were used to assess the quality of sea and bottom sediment water sampled at 8 stations and the specific activities of 8 enzymes determined for the liver and gill tissues of the mussel Crenomytilus grayanus can be a useful indicator of marine pollution.
Phosphatases and phosphodiesterases isolated from the red king crab (Paralithodes camtschatica) hepatopancreas
Five enzymes have been isolated from the hepatopancreas of the red king crab Paralithodes camtschatica by means of ion exchange and gel chromatography; the AcP, AcPD, and AlkPD activities are tolerant of high ionic strength.
Two new sesterterpenoids, terretonins H and I, from the marine-derived fungus Aspergillus ustus
Two new sesterterpenoids, terretonins H and I, were isolated from the lipophilic extract of the marine-derived fungus Aspergillus ustus KMM 4664 and tested for cytotoxic and embryotoxic effects using sperm and developing embryos of the sea urchin Strongylocentrotus intermedius and human cancer cells.
Isolation, characterization and molecular cloning of Duplex-Specific Nuclease from the hepatopancreas of the Kamchatka crab
A new Duplex-Specific Nuclease from Kamchatka crab hepatopancreas is described, determining its primary structure and developing a preparative method for its purification, finding that DSN had unique substrate specificity, cleaving only DNA duplexes longer than 8 base pairs, or DNA in DNA-RNA hybrids.
Acceptor activity of valine tRNA modified with CME‐carbodiimide. Heterogeneity of modified tRNA
It was found recently in this laboratory that the valine-acceptor activity of unfractionated yeast tRNA was largely retained after extensive moditication’with CME-carbodiimide in the presence of Mg*+
Metabolites of the Marine Fungus Asperigillus varians KMM 4630
Microscopic marine fungi are rich sources of various biologically active compounds [1-3]. In searching for these compounds in fungi isolated frm various marine habitats, we observed that the
Indolic metabolites from the new marine bacterium Roseivirga echinicomitans KMM 6058T
N-Acetyl-(1) and N,N-diacetyl-(2) tryptamines were isolated from the butanol extract of culture medium of the new marine bacterium Roseivirga echinicomitans KMM 6058T. The structures of the compounds
Evaluation of the ecological state of the Sea of Japan and the Sea of Okhotsk using the DNase test system
A study of the state of the Russian coastal marine ecosystems of the Sea of Japan (the Tumen River mouth) and the Sea of Okhotsk (the eastern shelf of Sakhalin Island and the Sakhalin Gulf) and
Purification and Characteristics of Ca2+, Mg2+- and Ca2+, Mn2+-Dependent and Acid DNases from Spermatozoa of the Sea Urchin Strongylocentrotus intermedius
Mechanisms of the endonuclease cleavage of double-stranded DNA have been established for the three enzymes and the possible involvement of DNases from sea urchin spermatozoa in programmed cell death is discussed.