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Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza
BACKGROUND Influenza A virus subtype H1N1 with the H274Y mutation emerged and spread worldwide. However, the clinical effectiveness of the neuraminidase inhibitors, oseltamivir and zanamivir, has notExpand
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A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons.
BACKGROUND To compare the effectiveness of oseltamivir for treatment of influenza A and influenza B, we conducted a prospective, multicenter study of the 2003-2004 and 2004-2005 influenza seasons.Expand
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Clinical effectiveness of oseltamivir for influenza A(H1N1) virus with H274Y neuraminidase mutation.
OBJECTIVE To evaluate the clinical effectiveness of oseltamivir therapy started within 48h of the onset for influenza A(H1N1) virus with H274Y neuraminidase (NA) mutation. METHODS Virus wasExpand
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Longer virus shedding in influenza B than in influenza A among outpatients treated with oseltamivir.
OBJECTIVE To compare the persistence, susceptibility and resistance of influenza A and influenza B viruses in oseltamivir therapy in outpatients of various ages. METHODS Virus isolation was doneExpand
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A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B.
OBJECTIVE To compare the effectiveness of zanamivir with oseltamivir for influenza A and B. METHODS 1113 patients with influenza A or B were enrolled in the 2006-2007 influenza season. The durationExpand
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Immunomodulator Clarithromycin Enhances Mucosal and Systemic Immune Responses and Reduces Re-Infection Rate in Pediatric Patients with Influenza Treated with Antiviral Neuraminidase Inhibitors: A
Background/Aims Treatment with antiviral neuraminidase inhibitors suppresses influenza viral replication and antigen production, resulting in marked attenuation of mucosal immunity and mildExpand
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Effects of antiviral drugs on viral detection in influenza patients and on the sequential infection to their family members—serial examination by rapid diagnosis (Capilia) and virus culture
Abstract In Japan, it is not uncommon that academic facilities prohibit students from attending classes when influenza becomes epidemic. The vaccination must be a useful preventive weapon to minimizeExpand
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Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season.
BACKGROUND To evaluate the effectiveness of oseltamivir and amantadine for the treatment of influenza with respect to various clinical factors, a prospective multicenter study of the influenza seasonExpand
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Comparison of the clinical symptoms and the effectiveness of neuraminidase inhibitors for patients with pandemic influenza H1N1 2009 or seasonal H1N1 influenza in the 2007–2008 and 2008–2009 seasons
The clinical symptoms and effectiveness of neuraminidase inhibitors (NAI) have not been adequately compared among pandemic H1N1 2009 patients, seasonal H1N1 patients, and patients with H1N1 with theExpand
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Zanamivir treatment is equally effective for both influenza A and influenza B.
36.0 78.3 � 41.9 influenza A and patients with influenza B, respectively, who were not treated with antiinfluenza drugs [3]. Studies of in vitro antiviral activity of oseltamivir or zanamivir againstExpand
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