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Theaflavins enhance intestinal barrier of Caco-2 Cell monolayers through the expression of AMP-activated protein kinase-mediated Occludin, Claudin-1, and ZO-1
- Ha-Young Park, Y. Kunitake, N. Hirasaki, Mitsuru Tanaka, T. Matsui
- Biology, Medicine
- Bioscience, biotechnology, and biochemistry
- 2 January 2015
It was concluded that TFs could enhance intestinal barrier function by increasing the expression of TJ-related proteins through the activation of AMPK in Caco-2 cells. Expand
Inhibition of Glucose Transport by Tomatoside A, a Tomato Seed Steroidal Saponin, through the Suppression of GLUT2 Expression in Caco-2 Cells.
- Bao-Qin Li, Yusuke Terazono, +4 authors T. Matsui
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 1 February 2018
It is demonstrated for the first time that the nontransportable tomato seed steroidal saponin, tomatoside A, suppressed GLUT2 expression via PKC signaling pathway during the ASBT-influx/MRP2-efflux process in Caco-2 cells. Expand
Evaluating the Reduced Hydrophobic Taste Sensor Response of Dipeptides by Theasinensin A by Using NMR and Quantum Mechanical Analyses
It is demonstrated that theasinensin A (TSA) had a potential to form the complex with hydrophobic Trp-containing dipeptides, and to reduce their membrane potential by artificial-lipid membrane taste sensor and 1H-nuclear-magnetic resonance (NMR) spectroscopy. Expand