• Publications
  • Influence
New diprenylated dihyrochalcones from leaves of Artocarpus elasticus
Abstract Two new diprenylated dihydrochalcones, elastichalcone A 1 and elastichalcone B 2 and three known compounds were isolated from the leaves of Artocarpus elasticus. Their structures wereExpand
  • 13
  • 3
  • PDF
Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70,
BackgroundMitrella kentii (M. kentii) (Bl.) Miq, is a tree-climbing liana that belongs to the family Annonaceae. The plant is rich with isoquinoline alkaloids, terpenylated dihydrochalcones andExpand
  • 40
  • 2
  • PDF
β Mangostin suppress LPS-induced inflammatory response in RAW 264.7 macrophages in vitro and carrageenan-induced peritonitis in vivo.
ETHNOPHARMACOLOGICAL RELEVANCE The fruit hull of Garcinia mangostana Linn. has been used in traditional medicine for treatment of various inflammatory diseases. Hence, this study aims to investigateExpand
  • 27
  • 2
Two new xanthones from Artocarpus obtusus
Two new xanthones, pyranocycloartobiloxanthone A (1) and dihydroartoindonesianin C (2), were isolated from the stem bark of Artocarpus obtusus Jarrett by chromatographic separation. Their structuresExpand
  • 28
  • 2
  • PDF
Prenylated flavones from Artocarpus altilis
Six prenylated flavones, including one new compound, were isolated and identified from the stem bark extracts of Artocarpus altilis. The new prenylated flavone hydroxyartocarpin (1) was characterizedExpand
  • 14
  • 2
Involvement of NF-κB and Bcl2/Bax signaling pathways in the apoptosis of MCF7 cells induced by a xanthone compound Pyranocycloartobiloxanthone A.
The plant Artocarpus obtusus is a tropical plant that belongs to the family Moraceae. In the present study a xanthone compound Pyranocycloartobiloxanthone A (PA) was isolated from this plant and theExpand
  • 77
  • 1
  • PDF
α-Mangostin from Garcinia mangostana Linn: An updated review of its pharmacological properties
Abstract Over the past decades, various studies have highlighted the pure natural compound, α -mangostin as their main topic. The compound’s pre-clinical and pharmacological properties have beenExpand
  • 83
  • 1
  • PDF
Antiproliferative Activity of Xanthones Isolated from Artocarpus obtusus
An investigation of the chemical constituents in Artocarpus obtusus species led to the isolation of three new xanthones, pyranocycloartobiloxanthone A (1), dihydroartoindonesianin C (2), andExpand
  • 21
  • 1
  • PDF
Anticancer activity of a monobenzyltin complex C1 against MDA-MB-231 cells through induction of Apoptosis and inhibition of breast cancer stem cells
In the present study, we examined the cytotoxic effects of Schiff base complex, [N-(3,5-dichloro-2-oxidobenzylidene)-4-chlorobenzyhydrazidato](o-methylbenzyl)aquatin(IV) chloride, and C1 onExpand
  • 20
  • 1
  • PDF
Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens
Background Cratoxylum arborescens has been used traditionally in Malaysia for the treatment of various ailments. Methods α-Mangostin (AM) was isolated from C. arborescens and its cell death mechanismExpand
  • 16
  • 1
  • PDF