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YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase‐like activity
Yeast cells lacking the metacaspase‐encoding gene YCA1 (Δyca1) were compared with wild‐type (WT) cells with respect to the occurrence, nature and time course of acetic‐acid triggered death. We showExpand
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Guidelines and recommendations on yeast cell death nomenclature
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellularExpand
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Cytochrome c is released from coupled mitochondria of yeast en route to acetic acid‐induced programmed cell death and can work as an electron donor and a ROS scavenger
To gain insight into the processes by which acetic acid‐induced programmed cell death (AA‐PCD) takes place in yeast, we investigated both cytochrome c release from yeast mitochondria andExpand
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Acid stress adaptation protects Saccharomyces cerevisiae from acetic acid-induced programmed cell death.
In this work evidence is presented that acid stress adaptation protects Saccharomyces cerevisiae from acetic acid-mediated programmed cell death. Exponential-phase yeast cells, non-adapted or adaptedExpand
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Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid
Beyond its classical biotechnological applications such as food and beverage production or as a cell factory, the yeast Saccharomyces cerevisiae is a valuable model organism to study fundamentalExpand
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Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer
Epithelial-to-mesenchymal transition (EMT) allows epithelial cancer cells to assume mesenchymal features, endowing them with enhanced motility and invasiveness, thus enabling cancer dissemination andExpand
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Proteome and metabolome profiling of wild-type and YCA1-knock-out yeast cells during acetic acid-induced programmed cell death.
UNLABELLED Caspase proteases are responsible for the regulated disassembly of the cell into apoptotic bodies during mammalian apoptosis. Structural homologues of the caspase family (calledExpand
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D-Lactate transport and metabolism in rat liver mitochondria.
In the present study we investigated whether isolated rat liver mitochondria can take up and metabolize D-lactate. We found the following: (1) externally added D-lactate causes oxygen uptake byExpand
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The role of mitochondria in yeast programmed cell death
Mammalian apoptosis and yeast programmed cell death (PCD) share a variety of features including reactive oxygen species production, protease activity and a major role played by mitochondria. In viewExpand
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Catalase T and Cu, Zn‐superoxide dismutase in the acetic acid‐induced programmed cell death in Saccharomyces cerevisiae
To investigate the role of catalase and superoxide dismutase (SOD) in the acetic acid (AA) induced yeast programmed cell death (AA‐PCD), we compared Saccharomyces cerevisiae cells (C‐Y) and cellsExpand
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