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Abundance and Significance of Neuroligin-1 and Neurexin II in the Enteric Nervous System of Embryonic Rats
Aim. To investigate the abundance of neuroligin-1 and neurexin II in the enteric nervous system (ENS) of rats on different embryonic days and to explore their potential significance. Methods. TheExpand
Aberrant Distributions of Collagen I, III and IV in Hirschsprung's Disease.
  • N. Gao, J. Wang, +6 authors Aiwu Li
  • Medicine
  • Journal of pediatric gastroenterology and…
  • 13 January 2020
BACKGROUND Hirschsprung's disease (HSCR) is the most common congenital gut motility disorder, involving a severe anomaly of the enteric nervous system (ENS), and is characterized by functionalExpand
Weighted Gene Coexpression Network Analysis Reveals the Critical lncRNAs and mRNAs in Development of Hirschsprung's Disease.
Hirschsprung's disease (HSCR) is a common newborn defect. This study aimed to identify critical genes involved in the development of HSCR. Differently expressed genes (DEGs) of public data setExpand
Effect of Neuroligin1 and Neurexin1 on the Colonic Motility in a Mouse Model of Neuronal Intestinal Dysplasia
Aim To investigate the expressions of neuroligin1 (NL1) and neurexin1 (NX1) in a mouse model of neuronal intestinal dysplasia (Tlx2−/− mice) and to explore their effects on colonic motility. MethodsExpand
Down‐regulation of fibronectin and the correlated expression of neuroligin in hirschsprung disease
The goal of this study was to investigate the expression of fibronectin (FN) and the correlated abundance of neuroligins (NLs) in the enteric nervous system (ENS) and to find a novel diagnosticExpand
The inverse relationship between fibronectin and neuroligins in the embryonic rat colon
Our previous study identified that the abnormal expression of fibronectin (FN), neuroligin-1 (NL1) and neuroligin-2 (NL2) in the colons of children with Hirschsprung disease (HSCR), but theExpand
Increased Fibronectin Impairs the Function of Excitatory/Inhibitory Synapses in Hirschsprung Disease
Although approximately 50% of cases have a known genetic defect, the precise pathogenesis of Hirschsprung disease (HSCR) is still unclear. We recently reported that expression of fibronectin (FN),Expand