Share This Author
SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny
SEAVIEW and PHYLO_WIN are two graphic tools for X Windows-Unix computers dedicated to sequence alignment and molecular phylogenetics. SEAVIEW is a sequence alignment editor allowing manual or…
Biased gene conversion and the evolution of mammalian genomic landscapes.
The recent evidence for a GC-biased gene conversion process in mammals, and its consequences for genomic landscapes, molecular evolution, and human functional genomics are reviewed.
Population Size Does Not Influence Mitochondrial Genetic Diversity in Animals
It is shown that the widely used mitochondrial DNA marker does not reflect species abundance or ecology: mtDNA diversity is not higher in invertebrates than in vertebrates, in marine than in terrestrial species, or in small than in large organisms.
Strong variations of mitochondrial mutation rate across mammals--the longevity hypothesis.
It is proposed that natural selection tends to decrease the mitochondrial mutation rate in long-lived species, in agreement with the mitochondrial theory of aging.
Molecular phylogeny of Cyprinidae inferred from cytochrome b DNA sequences.
- J. Briolay, N. Galtier, R. Brito, Y. Bouvet
- BiologyMolecular phylogenetics and evolution
- 1 February 1998
Phylogenetic relationships between European cyprinids were investigated by comparing cytochrome b gene sequences from 29 species, among which 20 were newly sequenced, in the first molecularly based study of cyPRinid diversity.
Adaptive Protein Evolution in Animals and the Effective Population Size Hypothesis
- N. Galtier
- 29 November 2015
It is shown that adaptation is a major process in protein evolution across all phyla of animals: the proportion of amino-acid substitutions that occurred adaptively is above 50% in a majority of species, and reaches up to 90%.
Mitochondrial DNA as a marker of molecular diversity: a reappraisal
It is argued that mitochondrial DNA is not always clonal, far from neutrally evolving and certainly not clock‐like, questioning its relevance as a witness of recent species and population history and the great potential of accumulating mtDNA data for evolutionary and functional analysis of the mitochondrial genome.
Maximum-likelihood phylogenetic analysis under a covarion-like model.
- N. Galtier
- BiologyMolecular biology and evolution
- 1 May 2001
Here, a model allowing covarion-like evolution of DNA sequences is introduced, and this model allows the site-specific rate to vary between lineages by adding as few as two parameters to the widely used among-site rate variation model.
GC-content evolution in mammalian genomes: the biased gene conversion hypothesis.
This discrete description of Base composition is spatially structured in mammalian genomes and three major classes of genomic fragments with low, median, and high GC content, respectively, are defined.
Comparative population genomics in animals uncovers the determinants of genetic diversity
It is shown that the diversity of a species is predictable, and is determined in the first place by its ecological strategy, and demonstrates the influence of long-term life-history strategies on species response to short-term environmental perturbations.