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Maturation of circulating dendritic cells and imbalance of T-cell subsets in patients with squamous cell carcinoma of the head and neck
TLDR
The results suggest that the decreased proportion of circulating DCs and decreased HLA-DR expression in DCs may have a major impact on systemic immune responses in patients with SCCHN. Expand
CD47 Promotes Neuronal Development through Src- and FRG/Vav2-Mediated Activation of Rac and Cdc42
TLDR
It is indicated that CD47 promotes development of dendrites and axons in hippocampal neurons in a manner dependent, at least in part, on activation of Cdc42 and Rac mediated by Src as well as by FRG and Vav2. Expand
Relationships between regulatory T cells and CD8+ effector populations in patients with squamous cell carcinoma of the head and neck
TLDR
The balance between type 1 and type 2 T‐cell subsets in cancer patients is thought to modulate antitumor immunity and CD4+CD25+ regulatory T cells (Treg), which are potent inhibitors of antitumors immune responses, also play an invaluable role in maintaining immune homeostasis. Expand
Diagnosis of tumor in the nasal cavity and paranasal sinuses with [11C]choline PET: Comparative study with 2-[18F]fluoro-2-deoxy-d-glucose (FDG) PET
TLDR
PET with 11C-choline may be useful to diagnosis tumors in the nasal cavity and paranasal sinuses and statistical significance was found. Expand
Muscarine-Induced Increase in Frequency of Spontaneous EPSCs in Purkinje Cells in the Vestibulo-Cerebellum of the Rat
TLDR
Results indicate that ACh increases the firing frequency of granule cells by inhibiting IKSO, which in turn increases the frequency of sEPSCs in Purkinje cells in the rat vestibulo-cerebellum. Expand
Characterization of mutant mice that express polyglutamine in cerebellar Purkinje cells
TLDR
The results suggest that Purkinje cells with periplasmic inclusions were not apoptotic, but their functions were substantially impaired, which could contribute to the severe ataxic phenotype. Expand
Radiation therapy for T2N0 laryngeal cancer: A retrospective analysis for the impact of concurrent chemotherapy on local control.
TLDR
Conurrent CRT had a positive impact on the local control of T2N0 laryngeal cancer and the multivariate analysis revealed that the treatment method (RT alone vs. CRT) was the most significant risk factor that predicted recurrence after RT. Expand
Stress-Evoked Tyrosine Phosphorylation of Signal Regulatory Protein α Regulates Behavioral Immobility in the Forced Swim Test
TLDR
It is shown that mice expressing a form of SIRPα that lacks most of the cytoplasmic region manifest prolonged immobility (depression-like behavior) in the forced swim (FS) test, and tyrosine phosphorylation of SirPα is important for regulation of depression- like behavior in the response of the brain to stress. Expand
Primary tumor induces sentinel lymph node lymphangiogenesis in oral squamous cell carcinoma.
TLDR
It is suggested that in OSCC, the primary tumor actively induces lymphangiogenesis in SLNs prior to the onset of metastases, and where tumor-derived VEGF-C plays an important role. Expand
Changes in the characteristics of definite Meniere's disease over time in Japan: a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease
TLDR
The incidence of new cases of Meniere's disease in elderly patients aged 60 years or more was found to have increased over time after correction for age distribution in the overall population after changes in age distribution of the population over time. Expand
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