• Publications
  • Influence
Pituitary gland development and disease: from stem cell to hormone production.
Many aspects of pituitary development have become better understood in the past two decades. The signaling pathways regulating pituitary growth and shape have emerged, and the balancing interactionsExpand
  • 68
  • 4
Effects of oxidants and antioxidants on proliferation of endometrial stromal cells.
OBJECTIVE To evaluate the effects of oxidative stress and antioxidants on proliferation of endometrial stromal cells. DESIGN In vitro study. SETTING Academic laboratory. PATIENT(S) Women, withExpand
  • 85
  • 2
Pituitary gland and pregnancy.
The hypothalamic-pituitary-adrenal axis is central to mammalian reproductive function, including conception, pregnancy maintenance, parturition, and breastfeeding. Pregnancy is associated withExpand
  • 39
  • 2
Changes in the Expression of Steroidogenic and Antioxidant Genes in the Mouse Corpus Luteum During Luteolysis1
Abstract Luteal cell death plays a key role in the regulation of the reproductive process in all mammals. It is also known that prostaglandin (PG) F2α is one of the main factors that cause lutealExpand
  • 23
  • 2
Mevastatin inhibits proliferation of rat ovarian theca-interstitial cells by blocking the mitogen-activated protein kinase pathway.
OBJECTIVE To evaluate mechanisms involved in mevastatin-induced inhibition of proliferation of ovarian theca-interstitial cells. DESIGN In vitro study. SETTING Academic laboratory. ANIMAL(S)Expand
  • 27
  • 1
Role of GnRH-GnRH receptor signaling at the maternal-fetal interface.
OBJECTIVE To investigate the expression and function of GnRH and GnRH receptor (GnRHR) subtypes at the maternal-fetal interface. DESIGN In vitro experiments using freshly isolated human trophoblastExpand
  • 13
  • 1
Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis.
OBJECTIVE Statins reduce cardiovascular risks by improving hypercholesterolemia, reducing vascular smooth muscle proliferation, and ameliorating inflammation. Polycystic ovary syndrome (PCOS) isExpand
  • 77
Proliferation of ovarian theca-interstitial cells is modulated by antioxidants and oxidative stress.
BACKGROUND Maintenance of ovarian homeostasis requires precise regulation of proliferation of thecal- interstitial (T-I) cells. Recent evidence indicates that oxidative stress and antioxidantsExpand
  • 51
  • PDF
Cost-effectiveness of cytogenetic evaluation of products of conception in the patient with a second pregnancy loss.
OBJECTIVE To compare the cost of two strategies for managing the patient with recurrent pregnancy loss (RPL). DESIGN Cost analysis using a decision analytic model was used to compare obtaining anExpand
  • 39
Insulin and Oxidative Stress Modulate Proliferation of Rat Ovarian Theca-Interstitial Cells Through Diverse Signal Transduction Pathways1
Abstract Insulin and moderate oxidative stress stimulate proliferation of ovarian theca-interstitial cells. The effects of these agents on selected signal transduction pathways were examined. PD98059Expand
  • 26