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Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity.
TLDR
Current knowledge of CCHFV is summarized, summarizing its molecular biology, maintenance and transmission, epidemiology and geographic range, including an extensive discussion of C CHFV genetic diversity, including maps of the range of the virus with superimposed phylogenetic trees. Expand
The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket
TLDR
The crystal structure of the Chikungunya virus macro domain with an RNA trimer shows a binding mode utilizing the same adenine-binding pocket as ADP-ribose, but avoiding the AMP binding site, which is the sole common feature in all macro domains. Expand
Molecular epidemiology of Rabbit haemorrhagic disease virus.
TLDR
RHDV circulated as an apparently avirulent virus throughout Britain more than 50 years ago and more than 30 years before the disease itself was identified, based on molecular phylogenetic analysis of British and European RHDV sequences. Expand
Negevirus: a Proposed New Taxon of Insect-Specific Viruses with Wide Geographic Distribution
TLDR
Six novel insect-specific viruses, isolated from mosquitoes and phlebotomine sand flies collected in Brazil, Peru, the United States, Ivory Coast, Israel, and Indonesia, appear to form a new taxon, tentatively designated Negevirus. Expand
Chikungunya: Evolutionary history and recent epidemic spread.
TLDR
A series of mutations in the recently emerged Indian Ocean Lineage that has adapted the virus for transmission for the first time by the Aedes albopictus urban mosquito vector are discussed, and CHIKV is compared to other arboviruses with and without similar histories of urbanization. Expand
Chimeric alphavirus vaccine candidates for chikungunya.
TLDR
Chikungunya virus is an emerging alphavirus that has caused major epidemics in India and islands off the east coast of Africa since 2005 and importations into Europe and the Americas underscore the risk of endemic establishment elsewhere. Expand
Alphaviruses: population genetics and determinants of emergence.
TLDR
This review discusses the ecology, epidemiology and molecular virology of the alphaviruses, then focuses on three of the most important members of the genus: Venezuelan and eastern equine encephalitis and chikungunya viruses, with emphasis on their genetics and emergence mechanisms. Expand
Benign circulation of rabbit haemorrhagic disease virus on Lambay Island, Eire.
TLDR
The detection of antibodies and the disparate Lambay virus lineage in an apparently healthy and isolated wild rabbit population provides the most convincing evidence yet that at least some strains of RHDV can circulate harmlessly for long periods of time in wild rabbits possibly by producing persistent or latent infections. Expand
Characterization of a novel Negevirus and a novel Bunyavirus isolated from Culex (Culex) declarator mosquitoes in Trinidad.
TLDR
Isolation and characterization of these viruses increase the knowledge of the geographical distribution, diversity and host range of mosquito-specific bunyaviruses and negeviruses. Expand
Genome-Scale Phylogeny of the Alphavirus Genus Suggests a Marine Origin
TLDR
A robust and comprehensive phylogeny of the Alphavirus genus is produced, presenting a more complete evolutionary history of these viruses compared to previous studies based on partial sequences. Expand
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