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Oestrous cycles in Bos taurus cattle.
- N. Forde, M. Beltman, P. Lonergan, M. Diskin, J. Roche, M. Crowe
- Biology, Chemistry
- Animal reproduction science
- 1 April 2011
In postpartum cows resumption of regular oestrous cycles (in addition to uterine involution) is fundamental for re-establishment of pregnancy. Expand
Effect of increasing progesterone concentration from Day 3 of pregnancy on subsequent embryo survival and development in beef heifers.
- F. Carter, N. Forde, +7 authors P. Lonergan
- Biology, Medicine
- Reproduction, fertility, and development
- 3 April 2008
In conclusion, insertion of a PRID on Day 3 of the oestrous cycle increased serum progesterone concentrations on subsequent days, which, while having no phenotypic effect on embryonic development on Days 5 or 7, was associated with an increase in embryonic size on Days 13 and 16. Expand
Progesterone-Regulated Changes in Endometrial Gene Expression Contribute to Advanced Conceptus Development in Cattle1
Validation of a number of genes by quantitative real-time PCR indicated that P4 supplementation advances endometrial gene expression by altering the time (FABP, DGAT2, and MSTN) or duration (CRYGS) of expression pattern for genes that contribute to the composition of histotroph. Expand
Conceptus-Induced Changes in the Endometrial Transcriptome: How Soon Does the Cow Know She Is Pregnant?1
Results revealed for the first time that changes that occur in the endometrial transcriptome are independent of the presence of a conceptus until pregnancy recognition. Expand
Changes in the Endometrial Transcriptome During the Bovine Estrous Cycle: Effect of Low Circulating Progesterone and Consequences for Conceptus Elongation1
There is clear evidence that the temporal changes in the transcriptome of the endometrium of cyclic heifers are sensitive to circulating P4 concentrations in the first few days after estrus, which results in a suboptimal uterine environment with reduced ability to support conceptus elongation. Expand
Transcriptomic analysis of the bovine endometrium: What is required to establish uterine receptivity to implantation in cattle?
The successful establishment of pregnancy in cattle requires a sequence of key events to ensure appropriate maternally derived secretions, establish uterine receptivity to implantation as well as an adequate endometrial response to IFNT production. Expand
The effect of elevated progesterone and pregnancy status on mRNA expression and localisation of progesterone and oestrogen receptors in the bovine uterus.
Early post-ovulatory P(4) supplementation advances the disappearance of PGR protein from the luminal epithelium on days 5 and 7, and decreases ESR2 mRNA expression during the mid-luteal phase, but has no effect on PGR or ESR1 mRNA expression. Expand
Pivotal Role for Monocytes/Macrophages and Dendritic Cells in Maternal Immune Response to the Developing Embryo in Cattle1
- N. Mansouri-Attia, Lilian J Oliveira, +7 authors T. Fair
- Biology, Medicine
- Biology of reproduction
- 1 November 2012
It is proposed that in cattle, successful pregnancy establishment is associated with a dramatic regulation of the cytokine network, primarily by endometrial monocytes/macrophages and dendritic cells. Expand
Oviduct-Embryo Interactions in Cattle: Two-Way Traffic or a One-Way Street?1
Failure to detect changes in the oviduct transcriptome in the presence of a single embryo may be due to the effect being local and undetectable under the conditions of this study. Expand
Conceptus-derived prostaglandins regulate gene expression in the endometrium prior to pregnancy recognition in ruminants.
- T. Spencer, N. Forde, P. Dorniak, T. R. Hansen, Jared J Romero, P. Lonergan
- Biology, Medicine
- 1 October 2013
The hypothesis was that the ovoid conceptus exerts a local effect on the endometrium prior to maternal recognition of pregnancy on day 16 in cattle, and the effects of infusing PGs at the levels produced by the elongating day 14 conceptus into the uterine lumen of cyclic ewes on ISG expression in theendometrium were determined. Expand