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In vitro activity and mutagenicity of bisbenzylisoquinolines and quinones against Trypanosoma cruzi trypomastigotes
The accidental transmission of Chagas' disease by donor blood is recognized as a serious problem in the Latin America. This paper describes the screening of natural products as possible new… Expand
Characterization of the interaction of domain III of the envelope protein of dengue virus with putative receptors from CHO cells.
Domain III (DIII) of the envelope protein of dengue virus (DENV) contains structural determinants for the interaction with cellular receptors. In the present study a solid phase assay and recombinant… Expand
Novel interactions of domain III from the envelope glycoprotein of dengue 2 virus with human plasma proteins.
UNLABELLED Blood cells and plasma are important media for the four serotypes of dengue virus (DENV1-4) spreading into an infected person. Thus, interactions with human plasma proteins are expected to… Expand
Receptor-activated human α2-macroglobulin interacts with the envelope protein of dengue virus and protects virions from temperature-induced inactivation through multivalent binding.
- V. Huerta, Patricia Toledo, +10 authors G. Chinea
- Biology, Medicine
- The Journal of general virology
- 1 December 2014
Based on the hypothesis that interactions between virions and serum components may influence the outcome of dengue virus (DENV) infections, we decided to use affinity chromatography with domain III… Expand