N. Dousset

Publications96
h-index17
Citations1,202
Highly Influential Citations24
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Antioxidant and cytoprotective properties of high-density lipoproteins in vascular cells.
Beside their key role in the regulation of cholesterol homeostasis, HDL exhibit antioxidant and anti-inflammatory properties that participate to their general antiatherogenic effect. The purpose of… Expand
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Effect of Aluminium on Lipid Peroxidation of Human High Density Lipoproteins
We investigated the effect of aluminium (Al 3+ ) on lipid peroxidation and physico-chemical properties of high density lipoproteins (HDL) isolated from human plasma. Our results demonstrated that Al… Expand
  • 49
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Structural modifications of HDL and functional consequences.
High density lipoproteins (HDL) are susceptible to structural modifications mediated by various mechanisms including oxidation, glycation, homocysteinylation or enzymatic degradation. Structural… Expand
  • 148
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Reduced Na+ -K+ -ATPase Activity and Plasma Lysophosphatidylcholine Concentrations in Diabetic Patients
A fraction from normal human plasma inhibiting Na+ -K+ ATPase has been recently identified as lysophosphatidylcholine (LPC). The aim of this study was to investigate the existence of a relationship… Expand
  • 75
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Antioxidant properties of HDL in transgenic mice overexpressing human apolipoprotein A-II.
Transgenic mice overexpressing human apolipoprotein A-II (huapoA-II) display high VLDL and low HDL levels. To evaluate the antioxidant potential of huapoA-II enriched HDL, we measured the activities… Expand
  • 56
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Influence of low density lipoprotein from insulin-dependent diabetic patients on platelet functions.
In the present work we studied in vitro the action of low density lipoproteins (LDL) isolated from normolipemic insulin-dependent diabetic (IDDM) patients on transmembrane cation transport, nitric… Expand
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Increased susceptibility to lipid oxidation of low-density lipoproteins and erythrocyte membranes from diabetic patients.
The aim of the present study was to determine if low-density lipoproteins (LDLs) and red blood cell (RBC) membranes from diabetic patients present an increased susceptibility to lipoperoxidation,… Expand
  • 92
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Fluorescence analysis of lipoprotein peroxidation.
Publisher Summary Low-density lipoproteins (LDL) can be oxidized by transition metals, by cells including endothelial cells, smooth muscle cells, monocytes, macrophages, and fibroblasts, and also by… Expand
  • 52
  • 1
Lipoprotein peroxidation in adult psoriatic patients.
Psoriasis, a chronic inflammatory skin disease characterized by an aberration of lipid metabolism, has been associated with an increased risk for atherosclerosis. Since oxidatively modified… Expand
  • 25
  • 1
Effect of aluminium ions on liposomal membranes as detected by Laurdan fluorescence.
We report here an investigation of the influence of aluminium on iron-induced peroxidation in brain model membranes. Laurdan fluorescence emission spectra and generalised polarisation measurements… Expand
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