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Functional Bowel Disorders
The FBDSI can be used to select patients for research protocols and/or follow their clinical outcome or response to treatments over time to develop a functional bowel disorder severity index for research and clinical care.
Cortical activation during human volitional swallowing: an event-related fMRI study.
- S. Hamdy, D. Mikulis, N. Diamant
- Biology, PsychologyAmerican Journal of Physiology - Gastrointestinal…
- 1 July 1999
Activations were bilateral, but almost every region, particularly the premotor, insular, and frontal opercular cortices, displayed lateralization to one or the other hemisphere.
Defecography in normal volunteers: results and implications.
Normality was shown to encompass radiological features often considered pathological which overlap with reported pathological states, and the formation of rectocoeles during defecation was a very common finding in women.
AGA technical review on anorectal testing techniques.
Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders.
Further validation of the IBS-QOL: a disease-specific quality-of-life questionnaire
- D. Drossman, D. Patrick, S. Bangdiwala
- Medicine, PsychologyAmerican Journal of Gastroenterology
- 1 April 2000
The IBS-QOL is responsive to treatment in a referral-based clinical population of patients with functional bowel disorders and significantly differentiated Responders from Nonresponders for most of the variables tested.
Altered brain structure in irritable bowel syndrome: potential contributions of pre-existing and disease-driven factors.
It is reported that patients with IBS have increased hypothalamic gray matter, which may be related to the association among IBS, stress, and the hypothalamic-pituitary-adrenal axis.
Functional disorders of the anus and rectum
- W. Whitehead, A. Wald, N. Diamant, P. Enck, J. Pembérton, S. C. Rao
- Medicine, PsychologyGut
- 1 September 1999
The epidemiology of each functional anorectal disorders is defined and discussed, their pathophysiology is summarized and diagnostic approaches and treatment are suggested.
Further validation of the IBS-QOL: a disease-specific quality-of-life questionnaire.