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Metabolomics for bioactivity assessment of natural products
Natural products historically have been a rich source of lead molecules in drug discovery, based on their capability to create unique and diverse chemical structures. However, it is also true thatExpand
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Volatiles and aroma characterization of several lai (Durio kutejensis) and durian (Durio zibethinus) cultivars grown in Indonesia
Abstract Volatiles of six lai and four durian cultivars grown in Indonesia were analyzed using SPME/GC-MS. Total of 49 compounds in lai and 44 in durian were identified, including sulfurs, esters,Expand
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Adenosine A1 receptor binding activity of methoxy flavonoids from Orthosiphon stamineus.
Orthosiphon stamineus Benth. ( Orthosiphon Grandiflorus Bold. or Clerodendranthus spicatus Thunb.) is an Indonesian medicinal herb traditionally used for diseases such as hypertension, diabetes, andExpand
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Metabolomics for the rapid dereplication of bioactive compounds from natural sources
The introduction of high throughput screening in the 1990s aimed to shorten the drugs discovery route. To fully use its high potential, this technology requires a large number of compounds to screen.Expand
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Hyperglycemic control and diabetes complication preventive activities of Bawang Dayak (Eleutherine palmifolia L. Merr.) bulbs extracts in alloxan-diabetic rats
Bawang Dayak (Eleutherine palmifolia L. Merr.) is traditionally used to cure diabetes mellitus and other diseases by Dayak tribes in Kalimantan Island, Indonesia, despite there is no scientificExpand
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Methanol Extract of Coleus amboinicus (Lour) Exhibited Antiproliferative Activity and Induced Programmed Cell Death in Colon Cancer Cell WiDr
Coleus amboinicus(Lour) (CA) has been reported to possess many pharmacological activities. In this study, evaluation of cytotoxicity using brine shrimp lethality bioassay and MTT assay using WiDrExpand
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KAPASITAS ANTIOKSIDAN DAN INHIBITOR ALFA GLUKOSIDASE EKSTRAK UMBI BAWANG DAYAK [Antioxidant and Alpha-Glucosidase Inhibitory Properties of Bawang Dayak Bulb Extracts]
Bawang dayak (Eleutherine palmifolia) is an indigenous plant in Borneo traditionally used by Dayak tribes to treat any kind of degenerative deseases including diabetes mellitus. The purpose of thisExpand
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Comprehensive extraction method integrated with NMR metabolomics: a new bioactivity screening method for plants, adenosine A1 receptor binding compounds in Orthosiphon stamineus Benth.
A large number of plant metabolites has provided as an incomparable chemical source for drug development. However, the wide range of the polarity of metabolites has been a big obstacle for full useExpand
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Comprehensive review on herbal medicine for energy intake suppression
The obesity drug development is present not a bright and successful story. So far, drugs reported to be effective, either from synthetic or natural sources, mostly stimulated controversy because ofExpand
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