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A method for the solubilization of a (1----3)-beta-D-glucan isolated from Saccharomyces cerevisiae.
This report describes a method for the solubilization of a micro-particulate beta-D-glucan. Insoluble glucan is dissolved in methyl sulfoxide and urea (8M) and partially phosphorylated at 100Expand
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Biochemical characterization of Kupffer and parenchymal cells isolated from rat liver.
Abstract The ability to isolate Kupffer and parenchymal cells permitted chemical characterization of these two distinct cell types. The activities of such enzymes as acid phosphatase, betaExpand
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Development, physicochemical characterization and preclinical efficacy evaluation of a water soluble glucan sulfate derived from Saccharomyces cerevisiae.
This report describes the development, characterization and preclinical efficacy evaluation of water soluble glucan sulfate. Glucan sulfate was derived from insoluble beta-1,3-D-glucan isolated fromExpand
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Glucan stimulates production of antitumor cytolytic/cytostatic factor(s) by macrophages.
Glucan, a beta 1,3-linked polyglucose, is an effective macrophage activating and tumor-inhibitory agent. Previous studies indicate that glucan enhances macrophage-mediated tumoricidal activity. TheExpand
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Glucan-induced enhancement of host resistance to selected infectious diseases.
We conducted studies with mice, rats, and monkeys which demonstrated the ability of glucan to induce either nonspecific or specific enhancement of host resistance to infectious diseases. IntravenousExpand
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Reticuloendothelial Function and the Immune Response
Hyperphagocytic activity of the reticuloendothelial system induced in mice by the injection of glucan is associated with a significant increase in the primary and secondary immune responsiveness ofExpand
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Identification of a reticuloendothelial stimulating agent in zymosan.
The functional activity of the reticuloendothelial system (RES), as determined by the intravascular clearance of colloidal carbon, and the degree of induced RE hyperplasia were studied following theExpand
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Increased resistance to Staphylococcus aureus infection and enhancement in serum lysozyme activity by glucan.
Glucan is a potent reticuloendothelial stimulant whose immunobiological activity is mediated, in part, by an increase in the number and function of macrophages. In studying the role of glucan as aExpand
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Protective effect of glucan in experimentally induced candidiasis.
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