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Grouped-coordinate ascent algorithms for penalized-likelihood transmission image reconstruction
The new grouped-coordinate ascent (GCA) algorithms in the class overcome several limitations associated with previous algorithms, and it is shown that the GCA algorithms converge faster than the SCA algorithm, even on conventional workstations.
Penalized weighted least-squares image reconstruction for dual energy X-ray transmission tomography
Presents a dual-energy (DE) transmission computed tomography (CT) reconstruction method that features nonnegativity constraints in the density domain and a penalized weighted least squares (PWLS) objective function has been chosen to handle the non-Poisson noise added by amorphous silicon detectors.
List-mode maximum likelihood reconstruction of Compton scatter camera images in nuclear medicine
A Maximum Likelihood (ML) image reconstruction technique using list-mode data has been applied to Compton scattering camera imaging. List-mode methods are appealing in Compton camera image
Myocardial imaging with a radioiodinated norepinephrine storage analog.
Meta-iodobenzylguanidine (M-IBG), an iodinated aromatic analog of the hypotensive drug quanethidine, localizes in the heart of the rat, dog, and rhesus monkey and blocking studies with reserpine suggest that a major component of myocardial retention is sequestration within the norephinephrine storage vesicles of the adrenergic nerves.
Preconditioning methods for improved convergence rates in iterative reconstructions
To increase reconstruction speed, spatially invariant preconditioning filters that can be designed using the tomographic system response and implemented using 2-D frequency-domain filtering techniques have been applied.
SPECT Compton-scattering correction by analysis of energy spectra.
Preliminary results encourage us to believe that a method for correcting for Compton-scattering in a wide variety of objects can be found, thus helping to achieve quantitative SPECT.
Design and feasibility study of a single photon emission microscope system for small animal I-125 imaging
This system is based on the use of a very-high resolution gamma camera coupled to a converging non-multiplexing multiple pinhole collimator that enables one to "zoom" into a small local region inside the object to extract imaging information with a very high spatial resolution and a reasonable sensitivity for gamma rays emitted from this local region.
A modified uniform Cramer-Rao bound for multiple pinhole aperture design
This paper proposed to use a resolution constraint that is imposed on mean gradient vectors of achieved estimators and derived the minimum achievable variance for any estimator satisfies this resolution constraint.
3D image reconstruction for a Compton SPECT camera model
A mathematical model of the transition matrix of the camera which exploits symmetries by using an adapted spatial sampling pattern in the object domain which reduces the very high storage and computation requirement inherent to 3D reconstruction using transition matrix inversion methods.
Performance evaluation of a very high resolution small animal PET imager using silicon scatter detectors.
A prototype having sensitivity high enough for initial small animal images can be used for in vivo studies of small animal models of metabolism, molecular mechanism and the development of new radiotracers.