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The Taste of Monosodium Glutamate: Membrane Receptors in Taste Buds
Receptor proteins for photoreception have been studied for several decades. More recently, putative receptors for olfaction have been isolated and characterized. In contrast, no receptors for tasteExpand
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An Optimized Method for In Situ Hybridization with Signal Amplification That Allows the Detection of Rare mRNAs
In situ hybridization (ISH) using nonradioactive probes enables mRNAs to be detected with improved cell resolution but compromised sensitivity compared to ISH with radiolabeled probes. To detect rareExpand
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A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.
  • N. Chaudhari
  • Medicine, Biology
  • The Journal of biological chemistry
  • 25 December 1992
The skeletal muscle-specific dihydropyridine-sensitive calcium channel is a critical component of excitation-contraction coupling in skeletal muscle. A recessive mutation in mice, muscular dysgenesisExpand
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Genetic expression in the developing brain.
The adult mouse brain contains complex populations of polyadenylated [poly(A)+] and nonpolyadenylated [poly(A)-] messenger RNA's (mRNA's). These mRNA's are separate sequence populations, similar inExpand
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mRNA for cardiac calcium channel is expressed during development of skeletal muscle.
During the early development of skeletal muscle, cardiac isotypes of several contractile proteins are known to be transiently expressed. We report here that skeletal muscle developing in vivo, asExpand
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Specific absence of the alpha 1 subunit of the dihydropyridine receptor in mice with muscular dysgenesis.
Muscular dysgenesis is a lethal mutation in mice that results in a complete absence of skeletal muscle contraction due to the failure of depolarization of the transverse tubular membrane to triggerExpand
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Brain "identifier sequence" is not restricted to brain: similar abundance in nuclear RNA of other organs.
A repeated 82 base pair sequence in genomic DNA of the rat was previously proposed as being a control element governing brain (neuron) specific genetic expression. This intronic sequence, termed theExpand
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Restoration of normal function in genetically defective myotubes by spontaneous fusion with fibroblasts
MUSCULAR dysgenesis in mice is a genetic disease of skeletal muscle caused by the recessive mutation mdg (ref. 1). Muscle fibres in affected mice are paralysed because of the failure ofExpand
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The evolution of the long and short repetitive DNA sequences in sea urchins.
The rates of evolution of purified long and short repetitive DNA sequences were examined by hybridisation analysis between the DNAs from several species of sea urchins. We find that the rates ofExpand
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