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Adaptive Rescaling Maximizes Information Transmission
This work relates an adaptive property of a sensory system directly to its function as a carrier of information about input signals, and gives direct evidence that the scaling of the input/output relation is set to maximize information transmission for each distribution of signals. Expand
Synergy in a Neural Code
We show that the information carried by compound events in neural spike trainspatterns of spikes across time or across a population of cellscan be measured, independent of assumptions about whatExpand
Selective Adaptation in Networks of Cortical Neurons
The observation that selective adaptation arises naturally in a network of cortical neurons developing ex vivo indicates that this is an inherent feature of spontaneously organizing cortical networks. Expand
Genome-wide transcriptional plasticity underlies cellular adaptation to novel challenge
It is shown here that a global transcriptional reprogramming (>1200 genes) underlies the adaptation of cells to novel challenges and a large fraction of the responding genes is nonreproducible in repeated experiments. Expand
Universal protein fluctuations in populations of microorganisms.
It is shown here that protein distributions measured under a broad range of biological realizations collapse to a single non-gaussian curve under scaling by the first two moments, implying that protein fluctuations do not reflect any specific molecular or cellular mechanism. Expand
Synaptic Size Dynamics as an Effectively Stochastic Process
The findings show the strength of a simple low dimensional statistical model to quantitatively describe synapse size dynamics as the integrated result of many underlying complex processes. Expand
Synthetic Gene Recruitment Reveals Adaptive Reprogramming of Gene Regulation in Yeast
The results reveal heritable adaptation induced by the exposure to glucose and demonstrate that genetic regulatory networks have the potential to support highly demanding events of gene recruitment. Expand
Adaptive response by state-dependent inactivation
Under general conditions, regardless of the details of kinetics, molecule availability encodes an averaging over past activity and feeds back multiplicatively on the system output, giving rise to a variety of system-specific forms of adaptive response. Expand
Synaptic Tenacity or Lack Thereof: Spontaneous Remodeling of Synapses
Experimental results on spontaneous synaptic remodeling are reviewed, its relative contributions to totalaptic remodeling, its statistical characteristics, and its physiological importance are addressed. Expand
Individuality and slow dynamics in bacterial growth homeostasis
Surprisingly, it is found that each cell suppresses fluctuations with a different strength; this variability defines an “individual” behavior for each cell, which is inherited along many generations. Expand