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Anatomic pairing of afferent arterioles and renin cell distribution in rat kidneys.
Close afferent arteriolar (AA) connectivity is a prerequisite for hemodynamic interaction between superficial rat nephrons. Studies were conducted in rat, mouse, rabbit, and human renal vasculaturesExpand
Insulin-like growth factor-I restores microvascular autoregulation in experimental chronic renal failure.
Impairment of autoregulation (AR) is associated with accelerated progression of chronic renal failure (CRF). As the bioavailability of insulin-like growth factor-I (IGF-I) is low in CRF, weExpand
Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade.
Angiotensin II (Ang II) stimulates the release and gene expression of endothelin-1 in isolated vascular smooth muscle cells. In 47 Sprague-Dawley rats, we assessed the influence of concomitantExpand
Bosentan prevents preglomerular alterations during angiotensin II hypertension.
The present study was performed to characterize structurofunctional alterations of preglomerular vessels during chronic angiotensin II (Ang II)-induced hypertension (Ang II group: 400 ng x kg[-1] xExpand
New Method for Imaging Innervation of the Renal Preglomerular Vasculature. Alterations in Hypertensive Rats
Objective: To develop a new method for viewing adrenergic innervation along renal preglomerular vessels; to assess nerve densities and vascular lesions along arcuate arteries (ArcA), arcuate arterialExpand
Preglomerular sudanophilia in L-NAME hypertensive rats: involvement of endothelin.
To characterize alterations of renal vessels occurring during systemic hypertension elicited in rats by 5, 10, and 25 days of treatment by the nitric oxide synthase inhibitor N(G)-nitro-L-arginineExpand
Chronic L-NAME hypertension in rats and autoregulation of juxtamedullary preglomerular vessels.
The impact of chronic NG-nitro-L-arginine methyl ester (L-NAME)-induced hypertension (20 mg.kg-1.day-1 po, for 25 days) on pressure responsiveness was assessed in vessels ranging from arcuateExpand
Interaction between cGMP-dependent dilators and autoregulation in rat preglomerular vasculature.
The influence of guanosine 3',5'-cyclic monophosphate (cGMP)-dependent dilators on autoregulatory responses (AR) of arcuate arteries (ArcA) and afferent arterioles at early sites and atExpand
Branching patterns and autoregulatory responses of juxtamedullary afferent arterioles.
The spatial organization of autoregulatory responses (AR) was assessed in couples of afferent arterioles (AA), either grouped as anatomic pairs or branched sequentially along the same arcuateExpand
Nitric oxide and preglomerular vascular lesions in lyon spontaneously hypertensive rats.
Accumulation of Sudan black-stainable (SB+) lipids is a hallmark of the focal inflammato-proliferative lesions that develop along preglomerular vessels in N G-nitro-L-arginine methyl ester (L-NAME)Expand