N. Bibire

Publications68
h-index6
Citations159
Highly Influential Citations0
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Fast HPLC Method for the Determination of Piroxicam and its Application to Stability Study
A fast and robust RP-HPLC isocratic method was developed for determination of piroxicam in bulk materials and pharmaceutical formulations. Optimum separation of piroxicam and stress induced…
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A HPLC Method for the Determination of Bisoprolol in Tablets and its Application to a Bioequivalence Study
TLDR
This paper presents the results of a six-month study of the phytochemical fingerprinting technique, developed in Iasi during the period of May 21 to 29, 2013.
Toxicity, Biocompatibility, pH-Responsiveness and Methotrexate Release from PVA/Hyaluronic Acid Cryogels for Psoriasis Therapy
TLDR
The biocompatibility tests proved that the obtained cryogels showed significantly decreased toxicity and areBiocompatible.
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Chitosan-Graft-Poly(N-Isopropylacrylamide)/PVA Cryogels as Carriers for Mucosal Delivery of Voriconazole
TLDR
Overall results showed that the CS-g-PNIPAAm/PVA 75/25 hydrogel has the potential to be used as a smart polymeric vehicle for topical applications.
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A New Liquid Chromatography-Tandem Mass Spectrometry Method for Determination of Bisoprolol in Human Plasma Samples
TLDR
A new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the determination of bisoprolol in human plasma samples, using metoprool as internal standard and liquid-liquid extraction procedure.
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EFFECTS OF TWO IMIDAZOLINE RECEPTOR ANTAGONISTS IN SPONTANEOUS BEHAVIOUR IN RATS
TLDR
The treatment with both imidazoline receptor antagonists was associated with important sedative effects in the Actimeter test in rats, and the effects of idazoxan were more intense than those of efaroxan in this experimental behavioural model.
The Influence of the Preparation Method on the Characteristics of a New Cosmetic Gel Based on Hyaluronic Acid and Matrix-Forming Polymers
Because hyaluronic acid (HA) cosmetic gels are the most commonly used gels in the cosmetic industry, the purpose of this study was to develop a new gel formulation of HA in carboxymethyl cellulose…
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A New and Sensitive LC-MS/MS Method for the Determination of Clopidogrel in Human Plasma
TLDR
The proposed method has been validated for a linear range of 10-10000 mg/mL and the value of the regression coefficient was ≥0.99 and can be used for the therapeutic drug monitoring of clopidogrel.
[Membrane-selective electrode for atropine assay].
TLDR
This electrode was used with good results for quantitative assay by direct potentiometry and potentiometric titration of atropine sulphate from pharmaceutical formulations, and has a linear response in the concentration range of 10(-2)-10(-5) M atropin sulphate.
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Validation of a spectrophotometric assay method for bisoprolol using picric acid.
TLDR
The proposed and validated spectrophotometric method for the determination of bisoprolol is simple and cost effective.
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