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RT-qPCR assay for detection of British (B.1.1.7) and South Africa (B.1.351) variants of SARS-CoV-2
TLDR
A rapid, cost-effective and direct RT-qPCR method for detection of the two variants of concern of SARS-CoV-2, and may provide a basis for developing tools for the detection of additional variant of concern.
Chlorogenic acid attenuates high-carbohydrate, high-fat diet-induced cardiovascular, liver, and metabolic changes in rats.
TLDR
Chlorogenic acid decreased inflammation and fat deposition in the liver along with reduced plasma liver enzyme activities of obese rats but did not change the plasma lipid profile, and increased diversity of gut microbiota, which may improve overall metabolism in the body.
Green coffee ameliorates components of diet-induced metabolic syndrome in rats
TLDR
It is suggested that chlorogenic acids, trigonelline and diterpenoids in green coffee attenuate diet-induced abnormalities in heart and liver in high-carbohydrate high-fat diet-fed rats.
Modulation of gut microbiota by spent coffee grounds attenuates diet‐induced metabolic syndrome in rats
TLDR
Intervention with spent coffee grounds may be useful for managing obesity and metabolic syndrome by altering the gut microbiota, thus increasing the value of this food waste.
Direct RT-qPCR assay for SARS-CoV-2 variants of concern (Alpha, B.1.1.7 and Beta, B.1.351) detection and quantification in wastewater
TLDR
Improved primers-probe sets for reverse transcriptase quantitative polymerase chain reaction (RT-qPCR) for SARS-CoV-2 detection including a rapid, cost-effective, and direct RT- qPCR method for detection of the two variants of concern.
Attenuation of Metabolic Syndrome by EPA/DHA Ethyl Esters in Testosterone-Deficient Obese Rats
TLDR
It is suggested that Omacor has potential to attenuate metabolic complications in prostate cancer patients with induced testosterone deprivation and reduce infiltration of inflammatory cells and collagen deposition in the heart, and reduced lipid accumulation and inflammatory cell infiltration without improving liver damage.
A new implantable tool for repeated assessment of supraventricular electrophysiology and atrial fibrillation susceptibility in freely moving rats.
TLDR
Evaluation of AF substrate in parallel with electrophysiological parameters validated the recent finding of a gradual increase in AF susceptibility over-time and demonstrated that this phenomenon is associated with an electrical remodeling process characterized by AERP shortening.
Adaptation of fuel selection to acute decrease in voluntary energy expenditure is governed by dietary macronutrient composition in mice
TLDR
An acute decrease in voluntary activity resulted in positive energy balance in mice on both diets, and decreased oxidation of the minor energy (macronutrients) fuel source, demonstrating that dietary macronutrient composition determines fuel utilization choices under conditions of acute changes in energetic demand.
CTRP6 rapidly responds to acute nutritional changes, regulating adipose tissue expansion and inflammation in mice.
TLDR
It is hypothesized that CTRP6, a C1QTNF family member, may constitute an early responder to acute nutritional changes in adipose tissue, with potential physiological roles, and is proposed as a gene that rapidly responds to acute changes in caloric intake, acting in acute over-nutrition to induce a "physiological inflammatory response" that limits adipose tissues expansion.
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