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Circular Dichroism: Principles and Applications
PARTIAL TABLE OF CONTENTS: Circular Dichroism: An Introduction (G. Snatzke). From Pasteur to Parity Nonconservation: Theories of the Origin of Molecular Chirality (S. Mason). Theoretical Approach toExpand
On the structure of endogenous ouabain.
TLDR
It turned out that the structural analysis had been complicated by a facile ouabain-borate complexation in borosilicate glassware, so it is not surprising that the polyhydroxylated ouABain molecule serves as a polydentate ligand to inorganic species. Expand
Physicochemical characterization of a ouabain isomer isolated from bovine hypothalamus.
Recent reports have shown the presence of a ouabain-like inhibitor of Na+/K(+)-ATPase in humans. We have purified a bovine hypothalamic Na+/K(+)-ATPase inhibitory factor (HIF) by using affinityExpand
Structures of two bacteriohopanoids with acyclic pentol side-chains from the cyanobacterium Nostoc PCC 6720
Two bacteriohopanepentols 2 and 3 have been isolated from the cyanobacterium Nostoc PCC 6720. Their structures were elucidated by 1H, 13C-NMR and mass spectrometry. The absolute configurations of theExpand
Application of electronic circular dichroism in configurational and conformational analysis of organic compounds.
TLDR
The discussion focuses on the application of ECD, also in combination with other methods, in structural analysis of organic compounds, including host-guest complexes, and will emphasize the importance of the interplay between configurational and conformational factors. Expand
Comprehensive Chiroptical Spectroscopy
Absolute configurations of fungal and plant metabolites by chiroptical methods. ORD, ECD, and VCD studies on phyllostin, scytolide, and oxysporone.
TLDR
This study shows that in the case of flexible and complex natural products only a concerted application of more than a single chiroptical technique permits unambiguous assignment of absolute configuration. Expand
Broad-spectrum antimicrobial activity of hemoglobin.
TLDR
It has been possible to map specific regions of the human hemoglobin molecule that are responsible for significant antimicrobial activity and it is conceivable that, in addition to its role in oxygen transport, hemoglobin functions as an important multi-defense agent against a wide range of microorganisms. Expand
Solution and biologically relevant conformations of enantiomeric 11-cis-locked cyclopropyl retinals.
TLDR
The chromophore sinks into the N-terminal of the opsin receptor from the side of the 4-methylene and 15-aldehyde, and that the binding cleft accommodates 11-cis-retinal with a slightly positive twist around C12/C13. Expand
SP-303, an antiviral oligomeric proanthocyanidin from the latex of Croton lechleri (Sangre de Drago).
TLDR
A variety of toxicological evaluations demonstrated the safety of SP-303, particularly orally, which was predictable, since condensed tannins are a common dietary component, and the larger proanthocyanidins as a class have high antiviral activity, whereas most of the monomers are inactive. Expand
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