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Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
TLDR
The results support a revision of the NeuPSIG recommendations for the pharmacotherapy of neuropathic pain and allow a strong recommendation for use and proposal as first-line treatment in neuropathicPain for tricyclic antidepressants, serotonin-noradrenaline reuptake inhibitors, pregabalin, and gabapentin. Expand
Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)
TLDR
The 10‐item questionnaire developed in the present study constitutes a new diagnostic instrument, which might be helpful both in clinical research and daily practice and found that a relatively small number of items are sufficient to discriminate neuropathic pain. Expand
EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision
TLDR
This second European Federation of Neurological Societies Task Force aimed at updating the existing evidence about the pharmacological treatment of neuropathic pain since 2005. Expand
Development and validation of the Neuropathic Pain Symptom Inventory
TLDR
The psychometric properties of the NPSI suggest that it might be used to characterize subgroups of neuropathic pain patients and verify whether they respond differentially to various pharmacological agents or other therapeutic interventions. Expand
Prevalence of chronic pain with neuropathic characteristics in the general population
TLDR
A higher prevalence of chronic pain with neuropathic characteristics was associated with middle age (50–64 years), manual professions and those living in rural areas, and it was more frequently located in the lower limbs and its intensity and duration were higher in comparison with chronic pain without neuropathy characteristics. Expand
EFNS guidelines on pharmacological treatment of neuropathic pain
TLDR
Evaluated trials provide level A evidence for the efficacy of tricyclic antidepressants, gabapentin, pregabalin and opioids, with a large number of class I trials, followed by topical lidocaine and the newer antidepressants venlafaxine and duloxetine. Expand
NeuPSIG guidelines on neuropathic pain assessment
TLDR
Screening questionnaires are suitable for identifying potential patients with neuropathic pain, but further validation of them is needed for epidemiological purposes and quantitative sensory testing is recommended for selected cases in clinic, including the diagnosis of small fiber neuropathies and for research purposes. Expand
Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy
TLDR
The results clearly show that the neuropathy produces abnormal pain‐related disorders in the rat, which are reminiscent of those observed in some human neuropathies. Expand
EFNS guidelines on neuropathic pain assessment
TLDR
This review led to the development of guidelines to be used in the management of patients with neuropathic pain, and the simplest psychometric scales and quality of life measures are probably the best methods. Expand
Using screening tools to identify neuropathic pain
TLDR
This work states that the treatment of chronic pain should be directed towards specific management strategies for neuropathic pain, and that specific management techniques should be applied to tackle these strategies. Expand
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