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An improved rat brain-tumor model.
The widely used intracerebral tumor implantation method by freehand injection into parietal or hippocampal areas of the rat brain has proven inadequate for reliable experimental therapeutic studies.… Expand
The morphogenesis of hydranencephaly.
- J. Halsey, N. Allen, H. Chamberlin
- Biology, Medicine
- Journal of the neurological sciences
- 1 February 1971
Abstract Hydranencephaly may result from any of a variety of destructive or developmental abnormalities which may act to produce the defect at any time from the end of the 3rd month of gestation to… Expand
Further observations on the nature of prosopagnosia
Two new cases of prosopagnosia are described and compared with pertinent clinical material from the English language literature. The interpretation of this disorder most compatible with the clinical… Expand
CYTOCHROME OXIDASE IN HUMAN BRAIN TUMOURS *
- N. Allen
- Chemistry, Medicine
- Journal of neurochemistry
- 1 December 1957
THE investigation reported in this communication has been undertaken for two principal reasons. The first aim has been to estimate the activity of an enzyme important to biological oxidations in a… Expand
CSF β-Glucuronidase Assay in the Diagnosis of Neoplastic Meningitis
• The clinical value of CSF β-glucuronidase assay in the differential diagnosis of chronic meningitis has been investigated over the past 20 years. Significant ( P
The effect of dimethyl sulfoxide on gray matter injury in experimental spinal cord trauma.
The possible effect of dimethyl sulfoxide upon the development of lesions in the gray matter after experimental spinal cord trauma has been investigated with the use of cytochrome oxidase assay and… Expand
Inhibition of Na+-K+-activated ATPase activity following experimental spinal cord trauma.
The specific activity of the membrane-bound enzyme, Na+-K+-activated adenosine triphosphatase (ATPase), has been shown to be decreased following experimental impact injury (400 gm-cm) to the spinal… Expand
MICROCHEMICAL AND HISTOCHEMICAL OBSERVATIONS IN A CASE OF KRABBE'S LEUKODYSTROPHY
Response of lysosomal hydrolases of dog spinal cord and cerebrospinal fluid to experimental trauma
Spinal cord damage was induced' in dogs by a 400 gm-centimeter force injury to assess an early release of lysosomal enzymes from traumatized cord. In whole cord homogenates, an early decrease in… Expand
ASSAY AND SUBCELLULAR LOCALIZATION OF THE ARYLSULPHATASES IN RAT BRAIN 1
—The properties and subcellular localization of type I (nitrophenyl) and type II (nitrocatechol) arylsulphatases were investigated in brain tissue of the rat, and optimal assay conditions were… Expand