• Publications
  • Influence
Molecular analysis of transport and oligomerization of the Yersinia enterocolitica adhesin YadA.
The Yersinia adhesin YadA is the prototype of a novel class of bacterial adhesins which form oligomeric lollipop-like structures and are anchored in the outer membrane by the C terminus. For YadA,Expand
  • 214
  • 30
Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series
Summary Background In December, 2019, the newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, causing COVID-19, a respiratory diseaseExpand
  • 180
  • 13
Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease
Loss of intestinal mucosa integrity is an important factor in the pathogenesis of inflammatory bowel disease (IBD). The aim of this study was to characterize expression changes and allelic variantsExpand
  • 162
  • 10
Contribution of trimeric autotransporter C-terminal domains of oligomeric coiled-coil adhesin (Oca) family members YadA, UspA1, EibA, and Hia to translocation of the YadA passenger domain and
The Oca family is a novel class of autotransporter-adhesins with highest structural similarity in their C-terminal transmembrane region, which supposedly builds a beta-barrel pore in the outerExpand
  • 49
  • 6
Expression of the meningococcal adhesin NadA is controlled by a transcriptional regulator of the MarR family
Two closely related pathogenic species have evolved in the genus Neisseria: N. meningitidis and N. gonorrhoeae, which occupy different host niches and cause different clinical entities. In contrastExpand
  • 26
  • 3
Rapid establishment of laboratory diagnostics for the novel coronavirus SARS-CoV-2 in Bavaria, Germany, February 2020
The need for timely establishment of diagnostic assays arose when Germany was confronted with the first travel-associated outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inExpand
  • 105
  • 2
  • PDF
Neisseria meningitidis adhesin NadA targets beta1 integrins: functional similarity to Yersinia invasin.
Meningococci are facultative-pathogenic bacteria endowed with a set of adhesins allowing colonization of the human upper respiratory tract, leading to fulminant meningitis and septicemia. TheExpand
  • 41
  • 2
Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020
Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratoryExpand
  • 18
  • 2
  • PDF
Exploring Anti-Bacterial Compounds against Intracellular Legionella
Legionella pneumophila is a ubiquitous fresh-water bacterium which reproduces within its erstwhile predators, environmental amoeba, by subverting the normal pathway of phagocytosis and degradation.Expand
  • 28
  • 2
  • PDF
Unusual, virulence plasmid-dependent growth behavior of Yersinia enterocolitica in three-dimensional collagen gels.
As a first approach to establishing a three-dimensional culture infection model, we studied the growth behavior of the extracellular pathogen Yersinia enterocolitica in three-dimensional collagenExpand
  • 23
  • 1