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Functional Characterization of Human Proton-Coupled Folate Transporter/Heme Carrier Protein 1 Heterologously Expressed in Mammalian Cells as a Folate Transporter
It is found that sulfasalazine is a potent inhibitor of hPCFT/HCP1, which would interfere with the intestinal absorption of MTX when coadministered in therapy for rheumatoid arthritis as well as folate. Expand
Purification and Characterization of an Extracellular Poly(l-Lactic Acid) Depolymerase from a Soil Isolate,Amycolatopsis sp. Strain K104-1
ABSTRACT Poly(l-lactic acid) (PLA)-degradingAmycolatopsis sp. strains K104-1 and K104-2 were isolated by screening 300 soil samples for the ability to form clear zones on the PLA-emulsified mineralExpand
Novel DPPH Radical Scavengers, Bisorbicillinol and Demethyltrichodimerol, from a Fungus.
In the screening program for antioxidants with DPPH radical scavenging activity, four yellowish compounds from the fermentation broth of Trichoderma sp. Expand
Phytochemical investigation of Tunisian Salicornia herbacea L., antioxidant, antimicrobial and cytochrome P450 (CYPs) inhibitory activities of its methanol extract
The chemical composition of Salicornia herbacea L. a food plant belonging to Chenopodiaceae was investigated based on its mineral composition, proteins and carbohydrates contents. The phenolicExpand
Cloning, Expression, and Cell Surface Localization of Paenibacillus sp. Strain W-61 Xylanase 5, a Multidomain Xylanase
It is shown that a xylan-degrading bacterium, W-61, excretes multiple xylanases, including xylanase 5 with a molecular mass of 140 kDa, and Paenibacillus sp. Expand
Evaluation of the Salmonella umu test with 83 NTP chemicals
The results of this study indicate that the umu test with a single Salmonella strain is a simple rapid system, with accuracy comparable to existing, more time‐consuming assays. Expand
Studies on the 1,1-Diphenyl-2-picrylhydrazyl Radical Scavenging Mechanism for a 2-Pyrone Compound
The radical scavenging mechanisms for the 2-pyrone compound, 4-hydroxy-3,6-dimethyl-2H-pyrane-2-one (1), and the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (4) in several solvent systems wereExpand
Antifungal Stress Compounds from Adzuki Bean, Vigna angularis, Treated with Cephalosporium gregatum Type B
Nine autifungal stress compounds were isolated and identified from the roots of adzuki bean ( Vigna angularis) that had been treated with Cephalosporium gregatum type B, which is an avirulent strainExpand
Mutations Suppressing the Loss of DegQ Function in Bacillus subtilis (natto) Poly-γ-Glutamate Synthesis
Interestingly, DegQ stabilizes phosphorylated DegS only in the presence of DegU, indicating a complex interaction of these three proteins, which is essential for the synthesis of extracellular poly-gamma-glutamate (γPGA). Expand
Novel laccases of Ganoderma sp. KU-Alk4, regulated by different glucose concentration in alkaline media
Physiological regulation of laccase production from Ganoderma sp. KU-Alk4, isolated in Thailand, was controlled by the initial glucose concentration in liquid culture. Different laccase isozymes wereExpand