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Red blood cells of several species are known to exhibit a ouabain-insensitive, anion-dependent K+ (Rb+) flux that is stimulated by cell swelling. We have used rabbit red cells to study the kinetics of activation and inactivation of the flux upon step changes in tonicity. Sudden hypotonic swelling (210 mosmol) activates the flux after a lag period of 10 min(More)
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