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A novel salt-tolerant protease produced by Aspergillus sp. FC-10 was purified to homogeneity through anion-exchange chromatography, preparative isoelectric-focusing electrophoresis, and gel filtration chromatography, with an overall recovery of 12.7%. This protease demonstrated an optimum pH range of 7.0–9.0 for activity, with a stable pH range of 5.0–9.0.(More)
While rabies is a significant public health concern in China, the epidemiology of animal rabies in the north and northwest border provinces remains unknown. From February 2013 to March 2014, seven outbreaks of domestic animal rabies caused by wild carnivores in Xinjiang (XJ) and Inner Mongolia (IM) Autonomous Regions, China were reported and diagnosed in(More)
Brain-derived neurotrophic factor (BDNF) plays an essential role in neuronal survival, proliferation, and synaptic remodeling and modulates the function of many other neurotransmitters. Additionally, it likely underlies neurodegenerative and psychiatric disorders, including alcohol dependence-related depression (AD-D). Here, we investigated the possible(More)
Superior cervical ganglia 10 (SCG10), as a microtubule (MT) destabilizer, maintains MT homeostasis and has a critical role in neuronal development, but its function in tumorigenesis has not been characterized. In the present study, we demonstrated that p21-activated kinase 4 (PAK4)-mediated SCG10 phosphorylation regulates MT homeostasis in metastatic(More)
Three mold strains isolated from soil in the Taipei area of Taiwan were compared with a commercial strain of Aspergillus oryzae for their proteolytic activities in an 18% NaCl aqueous solution system. Among these strains, the one subsequently identified and designated as Aspergillus sp. FC-10 produced protease with superior saline tolerance. In aflatoxin(More)
OBJECTIVE To determine subsets and functional characteristics of peripheral blood lymphocytes in men with infertility associated with anti-sperm antibodies. SUBJECTS AND METHODS Blood from 28 infertile men with anti-sperm antibodies and 34 fertile control males were tested for the lymphocyte subsets by indirect immunofluorescence and also for lymphocyte(More)
Peak bone mass is an important factor influencing the occurrence of osteoporosis and osteoporotic fracture in adulthood. We measured the areal bone mineral density (BMD) in a Chinese male infantry recruit group ranging in age from 17 to 23 years and subsequently assessed peak BMD at the lumbar vertebrae and hip. This study included 812 Chinese men of Han(More)
This study aims to investigate the value of high-resolution color Doppler ultrasonography (HR-CDU) in the evaluation of lower-extremity vasculopathy (LEV) and its related risk factors in type 2 diabetes mellitus (T2DM) patients. Two hundred forty T2DM patients were selected, who underwent lower-extremity arterial HR-CDU. The patients were divided into the(More)
Frank's lead system vectorcardiogram (VCG) was used to record the ventricular arrhythmias (VA) of different areas induced by pacing in 22 canines and by stimulating the epicardium of different areas in 8 patients of mitral stenosis during operation. The results showed that VCG can localize the origin of VA of 13 areas in canines and 9 areas in human. To(More)