N. Venugopal

K. Gangadhara Reddy1
V. Madhavi1
A. Vijaya Bhaskar Reddy1
1K. Gangadhara Reddy
1V. Madhavi
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2-N-butyl-4-spirocyclopentane-2-imidazoline-5-one has been highlighted as a potential genotoxic impurity in irbesartan. A sensitive LC-MS/MS method was developed and validated for the determination of 2-N-butyl-4-spirocyclopentane-2-imidazoline-5-one in irbesartan. Good separation between 2-N-butyl-4-spirocyclopentane-2-imidazoline-5-one and irbesartan was(More)
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