N V Ponomareva

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The application of DC-potential method for estimation of the rate of human brain energy metabolism opens new vistas for the development of theoretical and applied aspects of neurophysiology. Theoretically, the close connection of information and energy processes of the brain is essential for gaining an insight into the brain energy-formation unit. In(More)
Twenty first-order relatives of patients with early-onset Alzheimer's disease (AD; mean age 43.7 +/- 1.3 years), 20 patients with early-onset AD (mean age 65.7 +/- 0.9 years) and age-matched normal controls for the relatives and the patients underwent quantitative EEG (qEEG) examinations. In AD patients, delta and theta relative power values were increased(More)
Visual-evoked potentials (VEP) to a flash were studied in the first-order relatives of patients with Alzheimer's disease (AD) (mean age 38.2 +/- 2.6 years) in comparison with the patients (mean age 61.9 +/- 1.4 years) and age-matched normal controls. It was found that in the relatives of AD patients the latencies of N2, P3, N3 components were delayed(More)
Identification of preclinical markers is required for early diagnosis of Alzheimer's disease (AD) and cognitive dysfunction in advancing age. Quantitative EEG was examined in 145 individuals with AD, their unaffected relatives and unrelated individuals. The AD patients and their relatives were stratified by ApoE genotype. The resting EEG parameters were(More)
AIM to determine electrophysiological markers of middle cerebral artery blood flow velocity (BFV). PATIENTS AND METHODS transcranial Doppler registration of middle cerebral artery BFV and direct current (DC) potentials recording from surface of head were performed in 30 healthy volunteers. Analysis of correlation between the BFV and DC potentials was(More)
In patients with discirculatory encephalopathy the influence of verbal fluency test on the characteristics of cerebral perfusion, DC-potentials of the brain, as well as on blood pressure and heart rate was investigated. Two patterns of responses to the verbal fluency test were observed. The first one is the process of generalized activation, manifested by(More)
Associated changes in the characteristics of local cerebral blood flow (CBF) and slow brain electrical activity were studied in 40 patients with dyscirculatory encephalopathy. CBF and CBV (cerebral blood volume) values for the frontal and temporal cortex and basal ganglia positively correlated with the constant potential values in the central lead(More)
Patients with dyscirculatory encephalopathy (DE) were examined to elucidate interhemisphere relationships by recording brain constant potential (CP) and perfusion CT. Electrophysiological characteristics were shown to relate to local brain blood flow. Dispersion of intrehemisphere CP level in DE patients proved more pronounced than in healthy subjects.(More)
The dynamics of direct current potentials of the brain was studied in 10-11-year-old children during sustained attention to successive presentation of series of Shulte tables. Children were examined twice: before and after the series of training to fast reading. A gradual increase in the level of direct current potentials during sustained attention was(More)