N V Balenko

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A modifying influence of ortho-cresol (o-cresol) on the carcinogenic effect of benzo(a)pyrene (BaP) with combined oral administration to CC57Br mice had been found. During simultaneous administration of o-cresol (1 mg) and BaP (1 mg), the incidence of tumors, the multiplicity of tumors, and the degree of malignancy all increased, but the latency was(More)
Ortho-cresol (o-cresol) produces a modifying influence on the effect produced by benz/a/pyrene (BP) under mice CC57B exposure to the combined peroral administration of the two chemicals. A low-toxic dose of o-cresol (Img) abruptly activates the effect of the same dose of BP (1 mg) according to all parameters (increase of the frequency, coefficient of(More)
Overt dependence of lung tumour development on the values of the dose administered was shown in experiments on inbred white rats under intratracheal administration of various doses of dibenz (a, h) anthracene (DBA); minimal-effect dose and maximal no-effect dose of DBA were established in the experiment. A theoretically calculated allowable dose was used to(More)