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Cisplatin (cisplatinum (II) diamine dichloride) is an anticancer drug extensively used against a variety of cancers. Cisplatin chemotherapy is found to manifest dose-dependent nephrotoxicity. Depletion of renal antioxidant defence system has been suggested to be the main cause of cisplatin-induced nephrotoxicity. Our recent investigations revealed that(More)
Free radical mediated genetic instability is widely thought to be a major etiological factor for initiation of carcinogenesis. Mushrooms represent a largely untapped source of powerful new pharmaceutical products. In the present study, we examined the antiperoxidative, anti-inflammatory, and antimutagenic activities of the ethanol extract of the mycelium of(More)
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