N. S. Cherniack

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A mathematical model has been developed that includes sensations of breathlessness and a dynamic CO2 respiratory controller. Breathing sensations, which are represented as a discomfort index, are assumed to depend on arterial PCO2 level, automatic and wilful motor commands and mechanoreceptor feedback. Wilful control is assumed to arise from cortical(More)
Analytical and experimental results relating the interaction of functional residual capacity (FRC) and ventilation (V) on occlusion pressure in conscious man are presented. An analytical model was developed relating the airway pressure measured 100 ms after occlusion (P100) with FRC and V just before occlusion. By relating the change in diaphragmatic force(More)
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